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Cytotoxic norsesquiterpene peroxides from the endophytic fungus Talaromyces flavus isolated from the mangrove plant Sonneratia apetala.
TLDR
Four new norsesquiterpene peroxides, named talaperoxides A-D (1-4), as well as one known analogue, steperoxide B (5, or merulin A), have been isolated from a mangrove endophytic fungus, Talaromyces flavus, by elucidated mainly by 1D and 2D NMR.
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Antibacterial Bisabolane-Type Sesquiterpenoids from the Sponge-Derived Fungus Aspergillus sp.
TLDR
Four new bisabolane-type sesquiterpenoids, aspergiterpenoid A, 1, 2, 3, and 4 showed selective antibacterial activity against eight bacterial strains with the MIC values between 1.25 and 20.0 µM and the cytotoxic, antifouling, and acetylcholinesterase inhibitory activities of these compounds were examined.
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Bioactive hydroanthraquinones and anthraquinone dimers from a soft coral-derived Alternaria sp. fungus.
Five new hydroanthraquinone derivatives, tetrahydroaltersolanols C-F (1-4) and dihydroaltersolanol A (5), and five new alterporriol-type anthranoid dimers, alterporriols N-R (12-16), along with seven…
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SZ‐685C, a marine anthraquinone, is a potent inducer of apoptosis with anticancer activity by suppression of the Akt/FOXO pathway
TLDR
The aims of this study were to investigate the anti‐cancer activity of SZ‐685C, an anthracycline analogue isolated from marine‐derived mangrove endophytic fungi, and to explore the molecular mechanisms underlying such activity.
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Three Bianthraquinone Derivatives from the Mangrove Endophytic Fungus Alternaria sp. ZJ9-6B from the South China Sea
Three new bianthraquinone derivatives, alterporriol K (1), L (2) and M (3), along with six known compounds were obtained from extracts of the endophytic fungus Alternaria sp. ZJ9-6B, isolated from…
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A new xanthone derivative from the co-culture broth of two marine fungi (strain No. E33 and K38)
A new xanthone derivative, 8-hydroxy-3-methyl-9-oxo-9H-xanthene-1-carboxylic acid methyl ether (1), was isolated from the co-culture broth of two mangrove fungi (strain No. K38 and E33) isolated from…
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Bioactive indole alkaloids and phenyl ether derivatives from a marine-derived Aspergillus sp. Fungus.
TLDR
Two new prenylated indole alkaloids, 17-epi-notoamides Q and M (1 and 2), and two new phenyl ether derivatives, cordyols D and E (9 and 13), together with 10 known compounds were isolated from a marine-derived Aspergillus sp fungus and evaluated for their antibacterial activities in vitro.
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Asperterpenoid A, a new sesterterpenoid as an inhibitor of Mycobacterium tuberculosis protein tyrosine phosphatase B from the culture of Aspergillus sp. 16-5c.
TLDR
Asperterpenoid A exhibited strong inhibitory activity against Mycobacterium tuberculosis protein tyrosine phosphatase B (mPTPB) with an IC(50) value of 2.2 μM.
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The bioactive metabolites of the mangrove endophytic fungus Talaromyces sp. ZH-154 isolated from Kandelia candel (L.) Druce.
Bioactivity-directed fractionation of the extract of the mangrove endophytic fungus Talaromyces sp. ZH-154, which was isolated from the stem bark of Kandelia candel (L.) Druce, Rhizophoraceae,…
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Isocoumarins and benzofurans from the mangrove endophytic fungus Talaromyces amestolkiae possess α-glucosidase inhibitory and antibacterial activities
Six new isocoumarins, compounds 1–4 and 14–15, two new benzofurans, 16–17, along with nine known isocoumarin analogues, 5–13 were obtained from the mangrove endophytic fungus Talaromyces amestolkiae…
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