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The theoretical analysis of kinetic behaviour of "hysteretic" allosteric enzymes. I. The kinetic manifestations of slow conformational change of an oligomeric enzyme in the Monod, Wyman and Changeux
Abstract The curves of the time ( t ) dependent product (Pr) accumulation for Monod, Wyman & Changeux model (1965) , where the rate of installation of equilibrium between two conformational states ofExpand
The theoretical analysis of kinetic behaviour of "hysteretic" allosteric enzymes. II. The dissociating and associating enzymic systems in which the rate of installation of equilibrium between the
Abstract The present paper is concerned with the specificities of kinetic behaviour of dissociating enzyme systems where the equilibrium between oligomeric forms installs rather slowly in comparisonExpand
pH-dependent intermediate plateaux in the kinetics of the reaction catalyzed by "biosynthetic" L-threonine dehydratase of Escherichia coli K-12.
Abstract 1. 1.|A method for the determination of l -threonine dehydratase ( l -threonine hydro-lyase (deaminating), EC 4.2.1.16) activity, based on measurements of the amount of 2-oxobutyrate formedExpand
Kinetic manifestations of allosteric interactions in models of regulatory enzymes with "indirect" co-operativity.
Abstract The shape of the plots of initial reaction rate (ν) versus initial substrate concentration ([S]0) and versus initial concentration of allosteric effector ([F]0) for the model of allostericExpand
Purification of commercial preparations of NADP+ from AMP contamination.
A method for purification of commercial preparations of NADP+ from AMP contamination is described. The purification procedure includes one-step anion-exchange chromatography on Dowex-1 (formate) andExpand
Biosynthesis of Valine and Isoleucine in the Wheat Plant
As valine and isoleucine are essential amino-acids for animal organism, the mechanism of their biosynthesis in higher plants is of importance. Experiments carried out with micro-organisms have shownExpand
Studies of homogeneous "biosynthetic" L-threonine dehydratase from Escherichia coli K-12. Some kinetic properties and molecular multiplicity.
"Biosynthetic" L-threonine dehydratase (EC 4.2.1.16) was purified to a homogeneous state with 29% yield of total activity from Escherichia coli K-12. The homogeneity of the enzyme was shown byExpand
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