The choroid plexus-cerebrospinal fluid system: from development to aging.
- Z. Redzic, J. Preston, J. Duncan, A. Chodobski, J. Szmydynger-Chodobska
- BiologyCurrent Topics in Developmental Biology
- 2005
Molecular biology of the blood-brain and the blood-cerebrospinal fluid barriers: similarities and differences
- Z. Redzic
- BiologyFluids and Barriers of the CNS
- 18 January 2011
A number of specific transport proteins are expressed in brain capillary endothelial cells and CP epithelial cells that provide transport of nutrients and ions into the CNS and removal of waste products and ions from the brain extracellular fluids.
Polarized distribution of nucleoside transporters in rat brain endothelial and choroid plexus epithelial cells
- Z. Redzic, J. Biringer, S. Hladky
- BiologyJournal of Neurochemistry
- 1 September 2005
In both RBEC and RCPEC, adenosine uptake from the opposite chambers was Na+‐independent and partially inhibited by nitrobenzylthioinosine, indicating the presence of the equilibrative sensitive transporter rENT1.
Studies on the human choroid plexus in vitro
- Z. Redzic
- BiologyFluids and Barriers of the CNS
- 7 February 2013
The main characteristics and limitations of available in vitro methods to study human CPE could help researchers choose an appropriate experimental approach for a particular study.
The Role of Activated Microglia and Resident Macrophages in the Neurovascular Unit during Cerebral Ischemia: Is the Jury Still Out?
- Rawan Barakat, Z. Redzic
- BiologyMedical Principles and Practice
- 19 August 2015
Whether or not suppression of microglial activity after CI is beneficial for neurological outcome still remains unclear and current evidence suggests that no simple answer could be given to this question.
Brain to blood efflux transport of adenosine: blood–brain barrier studies in the rat
- A. Isakovic, N. Abbott, Z. Redzic
- BiologyJournal of Neurochemistry
- 1 July 2004
Kinetic parameters suggest that under conditions of elevated ISF adenosine in hypoxia/ischaemia, BBB efflux transport could increase up to 25% of the uptake into neurones/glia and become an important mechanism to oppose the rise in ISF concentration.
Expression of estrogen receptor α and β in rat astrocytes in primary culture: effects of hypoxia and glucose deprivation.
- M. Al-Bader, S. Malatiali, Z. Redzic
- BiologyPhysiological Research
- 2011
The observed decrease in ERα protein may limit estrogen-mediated signalling in astrocytes during hypoxia and recovery, which could play a role in the reduction of injury associated with cerebral ischemia in vivo.
Expression and functional activity of nucleoside transporters in human choroid plexus
- Z. Redzic, S. Malatiali, D. Grujičić, A. Isakovic
- BiologyCerebrospinal Fluid Research
- 11 January 2010
BackgroundHuman equilibrative nucleoside transporters (hENTs) 1-3 and human concentrative nucleoside transporters (hCNTs) 1-3 in the human choroid plexus (hCP) play a role in the homeostasis of…
Time Course of Hyperosmolar Opening of the Blood-Brain and Blood-CSF Barriers in Spontaneously Hypertensive Rats
- H. Al-Sarraf, Firuz Ghaaedi, Z. Redzic
- Biology, MedicineJournal of Vascular Research
- 28 December 2006
The time course of blood-brain barrier and blood-CSF barrier responses to hyperosmolar mannitol infusion during chronic hypertension was investigated using 14C-sucrose as a marker of barrier integrity to indicate disruption of both the BBB and the BCSFB after HMI in both SHR and WKY rats.
...
...