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Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China.
TLDR
The epidemiological and clinical characteristics of novel coronavirus (2019-nCoV)-infected pneumonia in Wuhan, China, and hospital-associated transmission as the presumed mechanism of infection for affected health professionals and hospitalized patients are described. Expand
A rapid advice guideline for the diagnosis and treatment of 2019 novel coronavirus (2019-nCoV) infected pneumonia (standard version)
  • Ying-hui Jin, Lin Cai, +43 authors Xing-Huan Wang
  • Medicine
  • Military Medical Research
  • 6 February 2020
TLDR
This rapid advice guideline is suitable for the first frontline doctors and nurses, managers of hospitals and healthcare sections, community residents, public health persons, relevant researchers, and all person who are interested in the 2019-nCoV. Expand
Clinical features and short-term outcomes of 221 patients with COVID-19 in Wuhan, China
TLDR
Patients with elder age, chronic comorbidities, blood leukocyte/lymphocyte count, procalcitonin level, co-infection and severe complications might increase the risk of poor clinical outcomes. Expand
Clinical course and outcome of 107 patients infected with the novel coronavirus, SARS-CoV-2, discharged from two hospitals in Wuhan, China
TLDR
A period of 7–13 days after illness onset is the critical stage in the COVID-19 course, which shows persistent lymphopenia, severe acute respiratory dyspnea syndrome, refractory shock, anuric acute kidney injury, coagulopathy, thrombocytopenia, and death. Expand
COVID-19-associated acute kidney injury: consensus report of the 25th Acute Disease Quality Initiative (ADQI) Workgroup
TLDR
This Consensus Statement from the Acute Disease Quality Initiative provides recommendations for the diagnosis, prevention and management of COVID-19 AKI and for areas of future research, with the aim of improving understanding of the underlying processes and outcomes for patients with CO VID- 19 AKI. Expand
Effects of Fluid Resuscitation With 0.9% Saline Versus a Balanced Electrolyte Solution on Acute Kidney Injury in a Rat Model of Sepsis*
TLDR
Volume resuscitation with Plasma-Lyte resulted in less acidosis and less kidney injury and improved short-term survival when compared with 0.9% saline in this experimental animal model of sepsis. Expand
Clinical features and outcomes of 221 patients with COVID-19 in Wuhan, China
TLDR
The COVID-19 epidemic spreads rapidly by human-to-human transmission, and patients with elder age, chronic comorbidities, blood leukocyte/lymphocyte count, procalcitonin level, co-infection and severe complications might increase the risk of poor clinical outcomes. Expand
Ensemble Models of Neutrophil Trafficking in Severe Sepsis
TLDR
A coarse-grained phenomenological model of the acute inflammatory response in CLP (cecal ligation and puncture)-induced sepsis in rats provides a platform for generating and testing hypotheses in silico, as well as motivating further experimental studies to advance understanding of the complex biological response to severe infection. Expand
Blood Purification and Mortality in Sepsis: A Meta-Analysis of Randomized Trials*
TLDR
A systematic review and meta-analysis of randomized trials to determine the association between various blood purification techniques and all-cause mortality in humans with sepsis found blood purifying techniques including hemoperfusion, plasma exchange, and hemofiltration with hem operfusion were associated with lower mortality in patients withSepsis. Expand
A mathematical model for fresh frozen plasma transfusion strategies during major trauma resuscitation with ongoing hemorrhage.
  • A. Ho, P. Dion, +4 authors Y. W. Ng
  • Medicine
  • Canadian journal of surgery. Journal canadien de…
  • 1 December 2005
TLDR
During resuscitation of a patient who has undergone major trauma, the equivalent of whole-blood transfusion is required to correct or prevent dilutional coagulopathy. Expand
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