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Processing of X-ray diffraction data collected in oscillation mode.
 Processing of X-ray diffraction data collected in oscillation mode.
Publisher Summary X-ray data can be collected with zero-, one-, and two-dimensional detectors, zero-dimensional (single counter) being the simplest and two-dimensional the most efficient in terms of… Expand
HKL-3000: the integration of data reduction and structure solution--from diffraction images to an initial model in minutes.
- W. Minor, M. Cymborowski, Z. Otwinowski, M. Chruszcz
- Biology, Medicine
- Acta crystallographica. Section D, Biological…
- 1 August 2006
A new approach that integrates data collection, data reduction, phasing and model building significantly accelerates the process of structure determination and on average minimizes the number of data… Expand
Multiparametric scaling of diffraction intensities.
- Z. Otwinowski, D. Borek, W. Majewski, W. Minor
- Medicine, Mathematics
- Acta crystallographica. Section A, Foundations of…
- 1 May 2003
A novel and general approach to scaling diffraction intensities is presented. The method minimizes the disagreement among multiple measurements of symmetry-related reflections using a stable… Expand
Structure and Control of the Actin Regulatory WAVE Complex
Members of the Wiskott–Aldrich syndrome protein (WASP) family control cytoskeletal dynamics by promoting actin filament nucleation with the Arp2/3 complex. The WASP relative WAVE regulates… Expand
THE CRYSTAL STRUCTURE OF THE BACTERIAL CHAPERONIN GROEL AT 2.8 ANGSTROMS
The crystal structure of the bacterial chaperonln GroEL at 2.8 Å
The crystal structure of Escherichia coli GroEL shows a porous cylinder of 14 subunits made of two nearly 7-fold rotationally symmetrical rings stacked back-to-back with dyad symmetry. The subunits… Expand
Structural basis for CoREST-dependent demethylation of nucleosomes by the human LSD1 histone demethylase.
Histone methylation regulates diverse chromatin-templated processes, including transcription. Many transcriptional corepressor complexes contain lysine-specific demethylase 1 (LSD1) and CoREST that… Expand
Secondary structure of Huntingtin amino-terminal region.
- Mee Whi Kim, Y. Chelliah, S. Kim, Z. Otwinowski, I. Bezprozvanny
- Medicine, Biology
- 9 September 2009
Huntington's disease is a genetic neurodegenerative disorder resulting from polyglutamine (polyQ) expansion (>36Q) within the first exon of Huntingtin (Htt) protein. We applied X-ray crystallography… Expand
WASH and WAVE actin regulators of the Wiskott–Aldrich syndrome protein (WASP) family are controlled by analogous structurally related complexes
- D. Jia, T. Gomez, +4 authors D. Billadeau
- Biology, Medicine
- Proceedings of the National Academy of Sciences
- 24 May 2010
We recently showed that the Wiskott–Aldrich syndrome protein (WASP) family member, WASH, localizes to endosomal subdomains and regulates endocytic vesicle scission in an Arp2/3-dependent manner.… Expand