• Publications
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Minocycline prevents nigrostriatal dopaminergic neurodegeneration in the MPTP model of Parkinson's disease
  • Y. Du, Z. Ma, +11 authors S. Paul
  • Medicine, Biology
  • Proceedings of the National Academy of Sciences…
  • 27 November 2001
Parkinson's disease is a chronic neurodegenerative disorder characterized by the loss of dopamine neurons in the substantia nigra, decreased striatal dopamine levels, and consequent extrapyramidalExpand
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Wnk1 kinase deficiency lowers blood pressure in mice: A gene-trap screen to identify potential targets for therapeutic intervention
The availability of both the mouse and human genome sequences allows for the systematic discovery of human gene function through the use of the mouse as a model system. To accelerate the geneticExpand
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Overexpression of Cdc25B, an androgen receptor coactivator, in prostate cancer
Cdc25B is a dual-specific phosphatase that mediates cell cycle progression by activating the cyclin-dependent kinases. It has been shown to possess oncogenic potential. To elucidate its potentialExpand
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Deregulated CDC25A expression promotes mammary tumorigenesis with genomic instability.
Checkpoint pathways help cells maintain genomic integrity, delaying cell cycle progression in response to various risks of fidelity, such as genotoxic stresses, compromised DNA replication, andExpand
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Cloning and expression of the cDNA of chicken cation-independent mannose-6-phosphate receptor.
  • M. Zhou, Z. Ma, W. Sly
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences…
  • 10 October 1995
We cloned and sequenced the 8767-bp full-length cDNA for the chicken cation-independent mannose-6-phosphate receptor (CI-MPR), of interest because, unlike its mammalian homologs, it does not bindExpand
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Induction of mammary gland hyperplasia in transgenic mice over-expressing human Cdc25B
Cdc25 A and B are dual-specificity phosphatases which have been implicated in neoplastic transformation. Although Cdc25A and Cdc25B have been found to be over-expressed in many cancer cell lines andExpand
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Inducible expression of FGF-3 in mouse mammary gland
Fibroblast growth factor-3 (FGF-3) is a crucial developmental regulator. Aberrant activation of this gene by mouse mammary tumor virus insertion results in pregnancy-responsive mammary tumorigenesis.Expand
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New Cytotoxic Secondary Metabolites from Marine Bryozoan Cryptosula pallasiana
A new sterol, (23R)-methoxycholest-5,24-dien-3β-ol (1), two new ceramides, (2S,3R,4E,8E)-2-(tetradecanoylamino)-4,8-octadecadien-l,3-diol (6) andExpand
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Microstructural and ultrastructural changes in the muscle cells of the oriental armyworm Mythimna separata Walker (Lepidoptera: Noctuidae) on treatment with wilforine.
This study investigated the mode of action of wilforine, an alkaloid with insecticidal properties, extracted from Tripterygium wilfordii Hook f., on the microstructure and ultrastructure of theExpand
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Ectopic expression of FGF-3 results in abnormal prostate and Wolffian duct development
To evaluate the effects of FGF-3 expression in the prostate and male reproductive tract, we employed a bitransgenic system to target FGF-3 to these organs. We present a first study that ectopic FGF-3Expand
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