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Pharmacokinetic and pharmacodynamic properties of oral L-citrulline and L-arginine: impact on nitric oxide metabolism.
- E. Schwedhelm, R. Maas, +6 authors R. Böger
- Chemistry, Medicine
- British journal of clinical pharmacology
Oral L-citrulline supplementation raises plasma L-arginine concentration and augments NO-dependent signalling in a dose-dependent manner, and a correlation between the increase of arginine/ADMA ratio and improvement of FMD is revealed. Expand
Preliminary Investigation of the Prevalence and Genotype Distribution of Giardia intestinalis in Dogs in Hungary
The results indicate, however, that dog giardiosis is highly prevalent in the studied geographical areas, but it doesn’t present severe zoonotic potential. Expand
Methods for a prompt and reliable laboratory diagnosis of Pompe disease: report from an international consensus meeting.
The Pompe Disease Diagnostic Working Group met to review data generated using the new methods, and to establish a consensus regarding the application of the methods for the laboratory diagnosis of Pompe disease. Expand
Prevalence of Pompe disease in 3,076 patients with hyperCKemia and limb-girdle muscular weakness
In a large cohort of unselected adult patients with hyperCKemia and/or limb-girdle muscular weakness, a prevalence of late-onset Pompe disease of 2.4%. Expand
Linked Common Polymorphisms in the Gelatinase A Promoter Are Associated with Diminished Transcriptional Response to Estrogen and Genetic Fitness*
- S. Harendza, D. Lovett, U. Panzer, Z. Lukacs, P. Kühnl, R. Stahl
- Biology, Medicine
- Journal of Biological Chemistry
- 6 June 2003
Gelatinase A is a known estrogen-responsive gene and the demonstration of a loss of function polymorphism within an operational estrogen receptor binding site associated with a decrease in genetic fitness underscores the biologic significance of promoter polymorphism analyses. Expand
Elimination of Dirofilaria (syn. Nochtiella) repens microfilariae in dogs with monthly treatments of moxidectin 2.5%/imidacloprid 10% (Advocate®, Bayer) spot-on
The data demonstrate the successful long-lasting elimination of microfilariae in dogs infected with zoonotic Dirofilaria repens and may be supposed that adult D. repens were killed based on the observation that no further microFilariae were seen up to 6 months after the end of the treatment period. Expand
Seroprevalence of some vector-borne infections of dogs in Hungary.
- R. Farkas, M. Gyurkovszky, Z. Lukacs, B. Aladics, N. Solymosi
- Biology, Medicine
- Vector borne and zoonotic diseases
- 10 April 2014
The first comprehensive study on the prevalence of canine vector-borne pathogens (Anaplasma phagocytophilum, Borrelia burgdorferi, Ehrlichia canis, and Dirofilaria immitis) was carried in Hungary because there were no data on their regional distribution and prevalence. Expand
Late-onset Pompe disease is prevalent in unclassified limb-girdle muscular dystrophies.
- N. Preisler, Z. Lukacs, +7 authors J. Vissing
- Molecular genetics and metabolism
- 1 November 2013
The findings indicate that a DBS should be considered early in the diagnostic work-up of patients with an LGMD phenotype, to rule out Pompe disease. Expand
Consensus recommendation for a diagnostic guideline for acid sphingomyelinase deficiency
An international panel of experts in the clinical and laboratory evaluation, diagnosis, treatment/management, and genetic aspects of ASMD convened to review the evidence base and share personal experience to develop a guideline for diagnosis of the various ASMD phenotypes. Expand
Hard Ticks Infesting Dogs in Hungary and their Infection with Babesia and Borrelia Species
A survey was carried out in Hungary to investigate the occurrence of hard tick species (Acari: Ixodidae) collected from dogs and Borrelia and Babesia spp. detected in them. In total, 1,424 ticks were… Expand