• Publications
  • Influence
RPN-6 determines C. elegans longevity under proteotoxic stress conditions
Organisms that protect their germ-cell lineages from damage often do so at considerable cost: limited metabolic resources become partitioned away from maintenance of the soma, leaving the ageingExpand
  • 284
  • 12
Coactivator/corepressor ratios modulate PR-mediated transcription by the selective receptor modulator RU486
Selective receptor modulators, such as the antiprogestin RU486, are known to exhibit partial agonist activities in a cell-type-dependent manner. Employing an in vitro chromatin transcription systemExpand
  • 146
  • 7
  • PDF
Organochlorine Pesticides in Consumer Fish and Mollusks of Liaoning Province, China: Distribution and Human Exposure Implications
Fish and mollusk samples were collected from markets located in 12 cities in Liaoning province, China, during August and September 2007, and 22 organochlorine pesticides (OCPs) were detected. DDT,Expand
  • 49
  • 7
The Expression Levels of Plasma micoRNAs in Atrial Fibrillation Patients
Background MicroRNA (miRNA) has been found in human blood. It has been increasingly suggested that miRNAs may serve as biomarkers for diseases. We examined the potential of circulating miRNA to serveExpand
  • 76
  • 6
  • PDF
Relaxation of the one child policy and trends in caesarean section rates and birth outcomes in China between 2012 and 2016: observational study of nearly seven million health facility births
Abstract Objective To examine how the relaxation of the one child policy and policies to reduce caesarean section rates might have affected trends over time in caesarean section rates and perinatalExpand
  • 58
  • 6
  • PDF
[The prevalence of HIV infection and the risk factors among MSM in 4 cities, China].
  • J. Xu, De-lin Han, +6 authors Z. Wu
  • Medicine
  • Zhonghua yu fang yi xue za zhi [Chinese journal…
  • 1 November 2010
OBJECTIVES To access the prevalence of HIV infection and the associated factors among urban MSM in China. METHODS Participants were recruited using respondent driven sampling and snowball samplingExpand
  • 30
  • 4
The Sex Ratio at Birth for 5,338,853 Deliveries in China from 2012 to 2015: A Facility-Based Study
Objective The accuracy of a population-based sex ratio at birth (SRB) in China has long been questioned. To depict a more accurate profile, the present study used data from a national surveillanceExpand
  • 13
  • 4
  • PDF
Sequential recruitment of steroid receptor coactivator-1 (SRC-1) and p300 enhances progesterone receptor-dependent initiation and reinitiation of transcription from chromatin
Employing a cell-free chromatin transcription system that recapitulates progesterone receptor (PR)-mediated transcription in vivo, we have investigated further the coactivator functions of steroidExpand
  • 100
  • 3
Steroid receptor coactivator-1 (SRC-1) enhances ligand-dependent and receptor-dependent cell-free transcription of chromatin.
Progesterone receptor (PR) functions as a transcription factor that modulates the transcription of target genes in response to progesterone and other signals. The transcriptional activity of PRExpand
  • 76
  • 3
A conserved ubiquitination pathway determines longevity in response to diet restriction
Dietary restriction extends longevity in diverse species, suggesting that there is a conserved mechanism for nutrient regulation and prosurvival responses. Here we show a role for the HECTExpand
  • 106
  • 3