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Complete genome analysis of the mandarin fish infectious spleen and kidney necrosis iridovirus.
The nucleotide sequence of the infectious spleen and kidney necrosis virus (ISKNV) genome was determined and found to comprise 111,362 bp with a G+C content of 54.78%. It contained 124 potential openExpand
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Haem-activated promiscuous targeting of artemisinin in Plasmodium falciparum
The mechanism of action of artemisinin and its derivatives, the most potent of the anti-malarial drugs, is not completely understood. Here we present an unbiased chemical proteomics analysis toExpand
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Structure and Evolutionary Origin of Ca2+-Dependent Herring Type II Antifreeze Protein
In order to survive under extremely cold environments, many organisms produce antifreeze proteins (AFPs). AFPs inhibit the growth of ice crystals and protect organisms from freezing damage. Fish AFPsExpand
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Characterization of a novel envelope protein WSV010 of shrimp white spot syndrome virus and its interaction with a major viral structural protein VP24.
White spot syndrome virus is one of the most serious viral pathogens causing huge mortality in shrimp farming. Here we report characterization of WSV010, a novel structural protein identified by ourExpand
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Shotgun Identification of the Structural Proteome of Shrimp White Spot Syndrome Virus and iTRAQ Differentiation of Envelope and Nucleocapsid Subproteomes *S
  • Z. Li, Q. Lin, +5 authors C. Hew
  • Biology, Medicine
  • Molecular & Cellular Proteomics
  • 1 September 2007
White spot syndrome virus (WSSV) is a major pathogen that causes severe mortality and economic losses to shrimp cultivation worldwide. The genome of WSSV contains a 305-kb double-stranded circularExpand
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Derivation and biological characterization of a molecular clone of SHIV(KU-2) that causes AIDS, neurological disease, and renal disease in rhesus macaques.
Previously, we described the derivation of a pathogenic strain of simian-human immunodeficiency virus (SHIV(KU-2)) consisting of the tat, rev, vpu, and env genes of HIV-1 (strain HXB2) in a geneticExpand
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Relations between BOLD fMRI-Derived Resting Brain Activity and Cerebral Blood Flow
Consistent resting brain activity patterns have been repeatedly demonstrated using measures derived from resting BOLD fMRI data. While those metrics are presumed to reflect underlying spontaneousExpand
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A cell-free stock of simian-human immunodeficiency virus that causes AIDS in pig-tailed macaques has a limited number of amino acid substitutions in both SIVmac and HIV-1 regions of the genome and
We have examined both the sequence changes in the LTR, gag, vif, vpr, vpx, tat, rev, vpu, env, and nef genes and the cell tropism of a cell-free stock of chimeric simian-human immunodeficiency virusExpand
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Test–retest stability analysis of resting brain activity revealed by blood oxygen level‐dependent functional MRI
To assess test–retest stability of four functional magnetic resonance imaging (fMRI)‐derived resting brain activity metrics: the seed‐region‐based functional connectivity (SRFC), independentExpand
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Differential transcriptomic analyses revealed genes and signaling pathways involved in iono-osmoregulation and cellular remodeling in the gills of euryhaline Mozambique tilapia, Oreochromis
BackgroundThe Mozambique tilapia Oreochromis mossambicus has the ability to adapt to a broad range of environmental salinities and has long been used for investigating iono-osmoregulation. However,Expand
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