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Alpha-enolase as a potential cancer prognostic marker promotes cell growth, migration, and invasion in glioma
BackgroundThe success of using glycolytic inhibitors for cancer treatment relies on better understanding the roles of each frequently deregulated glycolytic genes in cancer. This report analyzed the… Expand
The sponge microbiome project
Abstract Marine sponges (phylum Porifera) are a diverse, phylogenetically deep-branching clade known for forming intimate partnerships with complex communities of microorganisms. To date, 16S rRNA… Expand
Inhabitancy of active Nitrosopumilus-like ammonia-oxidizing archaea and Nitrospira nitrite-oxidizing bacteria in the sponge Theonella swinhoei
Nitrification directly contributes to the ammonia removal in sponges, and it plays an indispensable role in sponge-mediated nitrogen cycle. Previous studies have demonstrated genomic evidences of… Expand
Pharmacological and surgical treatment of obesity.
Hypoxia-induced PLOD2 promotes proliferation, migration and invasion via PI3K/Akt signaling in glioma
Gliomas are the most common form of malignant primary brain tumors with poor 5-year survival rate. Dysregulation of procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 (PLOD2) was observed in gliomas,… Expand
Advances in Marine Microbial Symbionts in the China Sea and Related Pharmaceutical Metabolites
- Z. Li
- Biology, Medicine
- Marine drugs
- 20 April 2009
Marine animals and plants such as sponges, sea squirts, corals, worms and algae host diverse and abundant symbiotic microorganisms. Marine microbial symbionts are possible the true producers or take… Expand
Mosquito Saliva Serine Protease Enhances Dissemination of Dengue Virus into the Mammalian Host
ABSTRACT Dengue virus (DENV), a flavivirus of global importance, is transmitted to humans by mosquitoes. In this study, we developed in vitro and in vivo models of saliva-mediated enhancement of DENV… Expand
Postsplenectomy Reactive Thrombocytosis
Thrombocytosis is frequently encountered as an incidental laboratory finding. The most common etiology is reactive (secondary) thrombocytosis due to infections, trauma, surgery, or occult malignancy.… Expand
The inhibitory effect of 15-R-LXA4 on experimental endometriosis.
- Q. Chen, W. Zhou, Demin Pu, Z. Li, Qiansheng Huang, Qingxi Chen
- European journal of obstetrics, gynecology, and…
- 1 August 2009
OBJECTIVE To determine the pro-resolution actions of 15-R-LXA(4) (LXA(4)) on endometriotic lesions and on the expression of interleukin-1beta (IL-1beta) and tumor necrosis factor-alpha (TNF-alpha) in… Expand
PROFEAT Update: A Protein Features Web Server with Added Facility to Compute Network Descriptors for Studying Omics-Derived Networks.
- P. Zhang, L. Tao, +7 authors Y. Chen
- Computer Science, Medicine
- Journal of molecular biology
- 3 February 2017
The studies of biological, disease, and pharmacological networks are facilitated by the systems-level investigations using computational tools. Expand