Rare primary extranodal lymphomas: diffuse large B-cell lymphomas of the genital tract
It is demonstrated that the rituximab and CHOP (cyclophosphamide, doxorubicin, vincristine, and prednisone; R-CHOP) chemoimmunotherapy is a good and tolerable treatment option in all cases.
Purification and characterization of a complex from placental syncytiotrophoblast microvillous membranes which inhibits the proliferation of human umbilical vein endothelial cells.
This study purified a complex from STBM which inhibits the proliferation of cultured human endothelial cells and identified two peaks of anti-proliferative activity specific to STBM.
Regulation and Function of Lentiviral Vector-Mediated TCIRG1 Expression in Osteoclasts from Patients with Infantile Malignant Osteopetrosis: Implications for Gene Therapy
- C. Thudium, I. Moscatelli, K. Henriksen
- Biology, MedicineCalcified Tissue International
- 19 August 2016
Infantile malignant osteopetrosis (IMO) is a rare, recessive disorder characterized by increased bone mass caused by dysfunctional osteoclasts. The disease is most often caused by mutations in the…
In vitro expansion of long‐term repopulating hematopoietic stem cells in the presence of immobilized Jagged‐1 and early acting cytokines
Targeting NSG Mice Engrafting Cells with a Clinically Applicable Lentiviral Vector Corrects Osteoclasts in Infantile Malignant Osteopetrosis.
Evidence is provided that transduction of IMO CD34+ cells with the clinically applicable EFS-T vector leads to full rescue of osteoclasts in vitro and partial rescue of fractures generated from NSG mice engrafting hematopoietic cells, which supports the continued clinical development of gene therapy for IMO.
Activity, disulphate mapping and structural modelling of the fifth domain of human β2‐glycoprotein I
Characterization of binding of human beta 2-glycoprotein I to cardiolipin.
- Z. Kertész, B. Yu, A. Steinkasserer, H. Haupt, A. Benham, Robert B Sim
- Biology, ChemistryBiochemical Journal
- 15 August 1995
beta 2-Glycoprotein I-cardiolipin complexes are reported to be a target antigen for the binding of a subset of anti-phospholipid antibodies. The characteristics of binding of beta 2-glycoprotein I to…
Neutrophil Functions and Autoimmune Arthritis in the Absence of p190RhoGAP: Generation and Analysis of a Novel Null Mutation in Mice
The results suggest that p190RhoGAP likely does not play a major indispensable role in β2 integrin-mediated in vitro and in vivo neutrophil functions or the effector phase of experimental autoimmune arthritis.
Antioxidant properties of di- and polyamines.