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DNAH1 gene mutations and their potential association with dysplasia of the sperm fibrous sheath and infertility in the Han Chinese population.
OBJECTIVE To investigate dynein, axonemal, heavy chain 1 (DNAH1) gene mutations that may be associated with dysplasia of the sperm fibrous sheath (DFS) and infertility in the Han Chinese population.… Expand
Expression signatures of long non-coding RNAs in early brain injury following experimental subarachnoid hemorrhage
- B. Zheng, Huailei Liu, +15 authors Shiguang Zhao
- Medicine, Biology
- Molecular medicine reports
- 11 March 2015
Subarachnoid hemorrhage (SAH) is an important cause of mortality in stroke patients. Long non-coding RNAs (LncRNAs) have important functions in brain disease, however their expression profiles in SAH… Expand
Hyperperfusion Syndrome After Stenting for Intracranial Artery Stenosis
Hyperperfusion syndrome (HPS) is a rare but potentially devastating postoperative complication developing after endarterectomy and carotid stenting. Limited information is available about this… Expand
Arsenic trioxide depletes cancer stem-like cells and inhibits repopulation of neurosphere derived from glioblastoma by downregulation of Notch pathway.
Notch signaling has been demonstrated to have a central role in cancer stem-like cells (CSLCs) in glioblastoma multiforme (GBM). We have recently demonstrated the inhibitory effect of arsenic… Expand
A novel TEX11 mutation induces azoospermia: a case report of infertile brothers and literature review
BackgroundTestis-expressed gene 11 (TEX11) is an X-linked gene and essential for meiotic recombination and chromosomal synapsis. TEX11 deficiency causes meiotic arrest and male infertility, and many… Expand
DNAH2 is a novel candidate gene associated with multiple morphological abnormalities of the sperm flagella
Multiple morphological abnormalities of flagella (MMAF) is one kind of severe teratozoospermia. Gene mutations reported in previous works only revealed the pathogenesis of approximately half of the… Expand
Role of autophagy in early brain injury after subarachnoid hemorrhage in rats
- H. Zhao, Z. Ji, D. Tang, C. Yan, Wenyang Zhao, Cheng Gao
- Biology, Medicine
- Molecular Biology Reports
- 1 February 2013
Early brain injury (EBI) occurred after aneurismal subarachnoid hemorrhage (SAH) strongly determined the patients’ prognosis. Autophagy was activated in neurons in the acute phase after SAH, while… Expand
Up-regulation of MIAT aggravates the atherosclerotic damage in atherosclerosis mice through the activation of PI3K/Akt signaling pathway
Abstract This study is performed to elucidate the role of long non-coding RNA myocardial infarction associated transcript (lncRNA MIAT) in vulnerable plaque formation in rats with atherosclerosis… Expand
Atorvastatin attenuates inflammation and oxidative stress induced by ischemia/reperfusion in rat heart via the Nrf2 transcription factor.
The role of atorvastatin in inflammation and oxidative stress induced by ischemia/reperfusion is currently not well understood. The aim of this study was toinvestigate whether atorvastatin modulates… Expand
Inhibition of autophagy by autophagic inhibitors enhances apoptosis induced by bortezomib in non-small cell lung cancer cells
- G. Wu, Haifeng Li, Z. Ji, Xiao-ming Jiang, Y. Lei, Mingli Sun
- Biology, Medicine
- Biotechnology Letters
- 22 February 2014
Bortezomib is a novel proteasome inhibitor that has promising antitumor activity against various cancer cells. We have assessed its antitumor activity in non-small cell lung cancer (NSCLC) A549 and… Expand