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Epidemiologic studies in a population-based childhood cancer registry in Northeast Hungary.
BACKGROUND Reports on the patterns of childhood cancer incidence are rare in Eastern Europe. To compare incidence rates and trends with international data, we processed records of the regionalExpand
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Incidence and Survival of Central Nervous System Involvement in Childhood Malignancies: Hungarian Experience
Direct extension and hematogenous metastasis of primary non-CNS malignant tumors to the CNS are rare complications in children. The authors analyzed the incidence and outcome of these complicationsExpand
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Ten-year Experiences on Initial Genetic Examination in Childhood Acute Lymphoblastic Leukaemia in Hungary (1993–2002). Technical Approaches and Clinical Implementation
A nationwide study was started in 1993 to provide genetic diagnosis for all newly diagnosed childhood ALL cases in Hungary using cytogenetic examination, DNA-index determination, FISH (aneuploidy,Expand
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Biclonal chromosomal aberrations in a child with myelodysplastic syndrome.
Hematological malignancies and premalignant diseases are generally of monoclonal origin. The prognostic and therapeutic significance of finding two genetically independent clones remains to beExpand
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High incidence of brain tumors of childhood in Hungary between 1989 and 2001.
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Expression and Prognostic Examination of Heat Shock Proteins (HSP 27, HSP 70, and HSP 90) in Medulloblastoma
Expression of heat shock proteins (HSPs) is of prognostic significance in several tumor types. HSP expression levels were determined in medulloblastomas and tested whether HSPs expression wasExpand
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mTOR Pathway As a Potential Target In a Subset of Human Medulloblastoma
As mammalian Target of Rapamycin (mTOR) plays role in protein synthesis and metabolism, mTOR pathway activation is involved in the pathogenesis of several types of tumors. Our aim was to elucidateExpand
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High expression of DNA methyltransferases in primary human medulloblastoma.
Epigenetic alterations have been implicated in cancer development. DNA methylation modulates gene expression, which is catalyzed by DNA methyltransferases (DNMTs). The objective of our study was toExpand
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Successful transfer of Eurosurveillance to ECDC
One of the first things the new European Centre for Disease Prevention and Control (ECDC) had to address in 2005 when the Centre was just being set up and operational was the requirement in its WorkExpand
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