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Antiproliferative effect of flavonoids and sesquiterpenoids from Achillea millefolium s.l. on cultured human tumour cell lines
- Boglárka Csupor-Löffler, Z. Hajdú, J. Hohmann
- Chemistry, BiologyPhytotherapy research : PTR
- 1 May 2009
The antiproliferative assay demonstrated that centaureidin is the most effective constituent of the aerial parts of yarrow: high cell growth inhibitory activities were observed especially on HeLa and MCF‐7 cells, which is the first report on the occurrence of seco‐pseudoguaianolides in the Achillea genus.
Antiproliferative constituents of the roots of Conyza canadensis.
Some of the active components of the isolated compounds proved to be substantially more potent against these cell lines than against noncancerous human foetal fibroblasts (MRC-5) and can therefore be considered selective antiproliferative natural products.
Diterpenoids and flavonoids from the fruits of Vitex agnus‐castus and antioxidant activity of the fruit extracts and their constituents
From the n‐hexane fraction of the fruits of Vitex agnus‐castus, eupatorin was identified for the first time, besides the known casticin, penduletin, vitexin and orientin, and the main flavonoid constituents of the EtOAc extract were assayed for antioxidant activity.
Bioactivity‐guided isolation of antiproliferative compounds from Centaurea arenaria
Different types of secondary metabolites were found to be responsible for the antitumour effects of the extracts; in addition to moderately active compounds (isokaempferid and moschamine), especially apigenin, eupatorin, arctigenin and arctiin, matairesinol and cnicin exert marked antitumours effects against these cell lines.
Integrated pest management of major pests and diseases in eastern Europe and the Caucasus
This book promotes Integrated Pest Management, to contribute to reduced reliance on pesticides and the avoidance of adverse impacts from pesticide use on the health and safety of farming communities,…
Ecdysteroids from Leuzea carthamoides
Antiproliferative activity of Artemisia asiatica extract and its constituents on human tumor cell lines.
The extract of Artemisia asiatica herb with antiproliferative activity against four human tumor cell lines (A2780, A431, HeLa, and MCF7) was analyzed by the MTT assay, and bioassay-directed…
Comprehensive two-dimensional liquid chromatography with parallel gradients for separation of phenolic and flavone antioxidants.
Effects of Chelidonium majus extracts and major alkaloids on hERG potassium channels and on dog cardiac action potential - a safety approach.
Investigation of the composition and stability of the essential oils of origanum vulgare ssp.vulgare L. andO. vulgare ssp.hirtum (Link) letswaart
SummaryThe essential oils ofOriganum vulgare L. ssp.hirtum (Link) letswaart andOriganum vulgare L ssp.vulgare (Fam. Lamiaceae), cultivated in Hungary, have been studied by GC and GC-MS and the…