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A haplotype of the CYP4A11 gene associated with essential hypertension in Japanese men
Essential hypertension is associated with the TC + TT genotype of rs1126742 in the human CYP4A11 gene and the A-T-G haplotype appears a useful genetic marker of essential hypertension in Japanese men. Expand
Haplotype-based case study of human CYP4A11 gene and cerebral infarction in Japanese subject
The GG genotype of rs9333025 could be a genetic marker for CI in Japanese men, and the T-C-G haplotype might also be a protective marker forCI in Japanese. Expand
Personalized antiplatelet therapy according to CYP2C19 genotype after percutaneous coronary intervention: a randomized control trial.
Personalized antiplatelet therapy according to CYP2C19 genotype after PCI can significantly decrease the incidence of major adverse cardiovascular events and the risk of 180-day ST in Chinese population. Expand
Polymorphisms in the SAA1/2 Gene Are Associated with Carotid Intima Media Thickness in Healthy Han Chinese Subjects: The Cardiovascular Risk Survey
Both rs12218 of the SAA1 gene and rs2468844 of SAA2 gene are associated with carotid IMT in healthy Han Chinese subjects. Expand
Age-related differences in postinfarct left ventricular rupture and remodeling.
Enhanced inflammatory response and subsequent increase in MMP-9 activity together with higher blood pressure are important factors responsible for the higher risk of cardiac rupture and more severe LV remodeling in the aged heart following acute MI. Expand
A haplotype of the CYP4F2 gene is associated with cerebral infarction in Japanese men.
The results of this study indicate that, in Japanese men, CI is associated with the G allele of rs2108622 and, in addition, that the T-C-G haplotype appears to be a useful genetic marker for CI. Expand
A Novel Polymorphism of the CYP4A11 Gene is Associated With Coronary Artery Disease
Background: CYP4A11 (cytochrome P450, family 4, subfamily A, polypeptide 11) converts arachidonic acid to 20-hydroxyeicosatetraenoic acid (20-HETE), which plays a crucial role in the modulation ofExpand
Interaction Between MMP-9 Gene Polymorphisms and Smoking in Relation to Myocardial Infarction in a Uighur Population
Findings suggest that MMP-9 −1562C>T polymorphism could be associated with the susceptibility to myocardial infarction in Chinese Uighur population, respectively. Expand
The clathrin adaptor Numb regulates intestinal cholesterol absorption through dynamic interaction with NPC1L1
Data show that Numb is a pivotal protein for intestinal cholesterol absorption and may provide a therapeutic target for hypercholesterolemia. Expand
Polymorphisms in the SAA1 gene are associated with ankle-to-brachial index in Han Chinese healthy subjects
CC genotypes in the SAA1 gene was associated with decreased ABI in Chinese Han subjects, which indicated that the carriers of CC genotype of rs12218 have high risk of peripheral arterial disease. Expand