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- Publications
- Influence
Particle size, surface coating, and PEGylation influence the biodistribution of quantum dots in living mice.
- M. L. Schipper, G. Iyer, +13 authors S. Gambhir
- Materials Science, Medicine
- Small
- 1 May 2008
This study evaluates the influence of particle size, PEGylation, and surface coating on the quantitative biodistribution of near-infrared-emitting quantum dots (QDs) in mice. Polymer- or… Expand
Diverse
Applications of Nanomedicine
- B. Pelaz, C. Alexiou, +83 authors W. Parak
- Materials Science, Medicine
- ACS nano
- 14 March 2017
The design and use of materials in the nanoscale size range for addressing medical and health-related issues continues to receive increasing interest. Research in nanomedicine spans a multitude of… Expand
Transferring Biomarker into Molecular Probe: Melanin Nanoparticle as a Naturally Active Platform for Multimodality Imaging
- Q. Fan, Kai Cheng, +8 authors Z. Cheng
- Chemistry, Medicine
- Journal of the American Chemical Society
- 7 October 2014
Developing multifunctional and easily prepared nanoplatforms with integrated different modalities is highly challenging for molecular imaging. Here, we report the successful transfer of an important… Expand
Molecular Optical Imaging with Radioactive Probes
Background Optical imaging (OI) techniques such as bioluminescence and fluorescence imaging have been widely used to track diseases in a non-invasive manner within living subjects. These techniques… Expand
A small-molecule dye for NIR-II imaging.
- Alexander L. Antaris, H. Chen, +13 authors H. Dai
- Materials Science, Medicine
- Nature materials
- 1 February 2016
Fluorescent imaging of biological systems in the second near-infrared window (NIR-II) can probe tissue at centimetre depths and achieve micrometre-scale resolution at depths of millimetres.… Expand
Fluorescent fructose derivatives for imaging breast cancer cells.
- J. Levi, Z. Cheng, +5 authors S. Gambhir
- Chemistry, Medicine
- Bioconjugate chemistry
- 20 April 2007
Breast cancer cells are known to overexpress Glut5, a sugar transporter responsible for the transfer of fructose across the cell membrane. Since Glut5 transporter is not significantly expressed in… Expand
microPET-Based Biodistribution of Quantum Dots in Living Mice
- M. L. Schipper, Z. Cheng, +7 authors S. Gambhir
- Chemistry, Medicine
- Journal of Nuclear Medicine
- 1 September 2007
This study evaluates the quantitative biodistribution of commercially available CdSe quantum dots (QD) in mice. Methods: 64Cu-Labeled 800- or 525-nm emission wavelength QD (21- or 12-nm diameter),… Expand
Carbon nanotubes as photoacoustic molecular imaging agents in living mice.
- A. de la Zerda, C. Zavaleta, +12 authors S. Gambhir
- Chemistry, Medicine
- Nature nanotechnology
- 1 September 2008
Photoacoustic imaging of living subjects offers higher spatial resolution and allows deeper tissues to be imaged compared with most optical imaging techniques. As many diseases do not exhibit a… Expand
Effects of nanoparticle size on cellular uptake and liver MRI with polyvinylpyrrolidone-coated iron oxide nanoparticles.
The effect of nanoparticle size (30-120 nm) on magnetic resonance imaging (MRI) of hepatic lesions in vivo has been systematically examined using polyvinylpyrrolidone (PVP)-coated iron oxide… Expand
Near-infrared fluorescent deoxyglucose analogue for tumor optical imaging in cell culture and living mice.
- Z. Cheng, J. Levi, +4 authors S. Gambhir
- Chemistry, Medicine
- Bioconjugate chemistry
- 21 April 2006
2-deoxy-2-[18F]fluoro-D-glucose ([18F]FDG) has extensively been used for clinical diagnosis, staging, and therapy monitoring of cancer and other diseases. Nonradioactive glucose analogues enabling… Expand