• Publications
  • Influence
Sensitive tumour detection and classification using plasma cell-free DNA methylomes
The use of liquid biopsies for cancer detection and management is rapidly gaining prominence1. Current methods for the detection of circulating tumour DNA involve sequencing somatic mutations usingExpand
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Profiles of Epigenetic Histone Post-translational Modifications at Type 1 Diabetes Susceptible Genes*
Background: Both genetic and epigenetic factors are implicated in Type 1 diabetes (T1D). Results: Variations in histone H3-lysine 9 acetylation are detected around the promoter/enhancer regions ofExpand
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Methylcrotonyl-CoA Carboxylase Regulates Triacylglycerol Accumulation in the Model Diatom Phaeodactylum tricornutum[C][W][OPEN]
The marine diatom Phaeodactylum tricornutum stores carbon and energy in the form of lipids, predominantly triacylglycerols (TAGs), making it an attractive system for biodiesel production, but theExpand
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JNK and ERK MAP kinases mediate induction of IL-1β, TNF-α and IL-8 following hyperosmolar stress in human limbal epithelial cells
Hyperosmolarity has been recognized to be a pro-inflammatory stress to the corneal epithelium. The cell signalling pathways linking hyperosmolar stress and inflammation have not been well elucidated.Expand
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The contribution of China’s emissions to global climate forcing
Knowledge of the contribution that individual countries have made to global radiative forcing is important to the implementation of the agreement on “common but differentiated responsibilities”Expand
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Assessing Forecast Accuracy Measures
This paper looks into the issue of evaluating forecast accuracy measures. In the theoretical direction, for comparing two forecasters, only when the errors are stochastically ordered, the ranking ofExpand
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Epigenomic profiling reveals an association between persistence of DNA methylation and metabolic memory in the DCCT/EDIC type 1 diabetes cohort
Significance Vascular complications are the main cause of morbidity and mortality in the diabetic population. Clinical trials of diabetic complications show a persistence of benefit from earlyExpand
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Sequencing and de novo assembly of a near complete indica rice genome
A high-quality reference genome is critical for understanding genome structure, genetic variation and evolution of an organism. Here we report the de novo assembly of an indica rice genome Shuhui498Expand
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Acetylome analysis reveals the involvement of lysine acetylation in photosynthesis and carbon metabolism in the model cyanobacterium Synechocystis sp. PCC 6803.
Cyanobacteria are the oldest known life form inhabiting Earth and the only prokaryotes capable of performing oxygenic photosynthesis. Synechocystis sp. PCC 6803 (Synechocystis) is a modelExpand
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Expression of barley SUSIBA2 transcription factor yields high-starch low-methane rice
  • J. Su, C. Hu, +9 authors C. Sun
  • Environmental Science, Medicine
  • Nature
  • 22 July 2015
Atmospheric methane is the second most important greenhouse gas after carbon dioxide, and is responsible for about 20% of the global warming effect since pre-industrial times. Rice paddies are theExpand
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