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Phosphotyrosyl Peptides Block Stat3-mediated DNA Binding Activity, Gene Regulation, and Cell Transformation*
Signal transducers and activators of transcription (STATs) comprise a family of cytoplasmic signaling proteins that participates in normal cellular responses to cytokines and growth factors.Expand
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Association of Mammalian Trp4 and Phospholipase C Isozymes with a PDZ Domain-containing Protein, NHERF*
  • Y. Tang, J. Tang, +5 authors M. Zhu
  • Chemistry, Medicine
  • The Journal of Biological Chemistry
  • 1 December 2000
Mammalian homologues of DrosophilaTrp have been implicated to form channels that are activated following the depletion of Ca2+ from internal stores. Recent studies indicate that actin redistributionExpand
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Mitochondria Localization and Dimerization Are Required for CIDE-B to Induce Apoptosis*
Cell death-inducingDFF45-like effector (CIDE)-B is a member of the novel family of apoptosis-inducing factors that share homology with the N-terminal region of DFF, the DNA fragmentation factor. TheExpand
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Embryonic Lethality and Defective Neural Tube Closure in Mice Lacking Squalene Synthase*
Squalene synthase (SS) catalyzes the reductive head-to-head condensation of two molecules of farnesyl diphosphate to form squalene, the first specific intermediate in the cholesterol biosyntheticExpand
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Unilateral low-frequency stimulation of central piriform cortex inhibits amygdaloid-kindled seizures in Sprague–Dawley rats
The central piriform cortex (cPC) is considered to be critically involved in the generation and propagation of kindled seizures. Our previous study found that low-frequency stimulation (LFS) of theExpand
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The Juxtamembrane, Cytosolic Region of the Epidermal Growth Factor Receptor Is Involved in Association with α-Subunit of Gs*
Previously, we have demonstrated that epidermal growth factor (EGF) can stimulate adenylyl cyclase activity via activation of Gs in the heart. Moreover, we have recently shown that Gsα isExpand
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Arg124Cys mutation of the TGFBI gene in 2 Chinese families with Thiel-Behnke corneal dystrophy.
OBJECTIVE To analyze transforming growth factor beta-induced (TGFBI) gene mutations in 2 Chinese families with Thiel-Behnke corneal dystrophy (TBCD). METHODS Forty-five individuals in 2 ChineseExpand
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Unilateral low-frequency stimulation of central piriform cortex delays seizure development induced by amygdaloid kindling in rats
Low-frequency stimulation of the kindling site interferes with the course of kindling epileptogenesis. The present study examined the effect of unilateral low-frequency stimulation of the centralExpand
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Ecdysteroid biosynthesis in the crustacean Y-organ and control by an eyestalk neuropeptide
The endocrine axis is described that controls growth, molting, and regeneration in crustaceans: The ecdysial glands (Y-organs), sources of ecdysteroid hormones, and eyestalk neurosecretory centers,Expand
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Folate-mediated poly(3-hydroxybutyrate-co-3-hydroxyoctanoate) nanoparticles for targeting drug delivery.
A novel targeting drug delivery system (TDDS) has been developed. Such a TDDS was prepared by W(1)/O/W(2) solvent extraction/evaporation method, adopting poly(3-hydroxybutyrate-co-3-hydroxyoctanoate)Expand
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