• Publications
  • Influence
Effect of nonylphenol on male reproduction: analysis of rat epididymal biochemical markers and antioxidant defense enzymes.
TLDR
NP treatment impairs spermatogenesis and has a cytotoxic effect on epididymal sperm and disrupts the prooxidant and antioxidant balance, which leads oxidative stress in epidIDymal sperms of rat.
The formulation of a nasal nanoemulsion zaleplon in situ gel for the treatment of insomnia
  • K. Hosny, Z. Banjar
  • Materials Science, Medicine
    Expert opinion on drug delivery
  • 18 July 2013
TLDR
The nasal NEG is a promising novel formula for zaleplon that has higher nasal tissue permeability and enhanced systemic bioavailability.
Phenolics from Garcinia mangostana alleviate exaggerated vasoconstriction in metabolic syndrome through direct vasodilatation and nitric oxide generation
TLDR
The phenolic compounds 2, 4, and 5 ameliorated the exaggerated vasoconstriction in MetS aortae through vasodilatation-NO generation mechanism.
Mangostanaxanthones III and IV: advanced glycation end-product inhibitors from the pericarp of Garcinia mangostana
TLDR
All of the isolated xanthones significantly inhibited both sugar (ribose) and dicarbonyl compound (methylglyoxal)-induced protein glycation in a dose-dependent manner, explained by the ability of the isolate to inhibit protein oxidation.
Phenolics from Garcinia mangostana Inhibit Advanced Glycation Endproducts Formation: Effect on Amadori Products, Cross-Linked Structures and Protein Thiols
TLDR
Investigation of the inhibitory effect of bioactive metabolites isolated from fruit hulls of Garcinia mangostana on AGE formation found phenolic compounds 1–4 inhibited AGEs formation at the levels of Amadori product and protein aggregation formation through saving protein thiol.
Solid lipid nanoparticles loaded with iron to overcome barriers for treatment of iron deficiency anemia
TLDR
Fe-SLNs could be a promising carrier for iron with enhanced oral bioavailability, in order to find an innovative way for alleviating the disadvantages associated with commercially available tablets.
New Cerebroside and Nucleoside Derivatives from a Red Sea Strain of the Marine Cyanobacterium Moorea producens
TLDR
The organic extract of the Red Sea cyanobacterium afforded one new cerebroside, mooreaside A, two new nucleoside derivatives, 3-acetyl-2′-deoxyuridine and 3-phenylethyl- 2′- de Oxyuridine, along with the previously reported compounds thymidine and 2,3-dihydroxypropyl heptacosanoate.
Protective effect of zingerone on increased vascular contractility in diabetic rat aorta.
TLDR
Zingerone ameliorates enhanced vascular contraction in diabetic aortae which may be mediated by its vasodilator effect through NO- and guanylate cyclase stimulation.
6-Gingerol alleviates exaggerated vasoconstriction in diabetic rat aorta through direct vasodilation and nitric oxide generation
TLDR
6-gingerol ameliorates enhanced vascular contraction in diabetic aortae, which may be partially attributed to its ability to increase the production of NO and stimulation of cyclic guanosine monophosphate.
Geraniol alleviates diabetic cardiac complications: Effect on cardiac ischemia and oxidative stress.
TLDR
Results obtained in this study suggest that geraniol provides a potent protective effect against cardiac dysfunction induced by diabetes, which could be attributed to its suppression of oxidative stress.
...
1
2
3
...