Amphiphilic Diblock Copolymer Compatibilizers and Their Effect on the Morphology and Performance of Polythiophene:Fullerene Solar Cells
- K. Sivula, Z. Ball, N. Watanabe, J. Fréchet
- Materials Science
- 19 January 2006
Addition of Metalloid Hydrides to Alkynes: Hydrometallation with Boron, Silicon, and Tin
This review covers the synthesis of isolabile vinylmetalloids through hydroboration, hydrosilylation, and hydrostannation, with special focus on recent developments, metal-catalyzed reactions, and…
Structure-selective modification of aromatic side chains with dirhodium metallopeptide catalysts.
The combination of peptide molecular recognition and residue-selective dirhodium catalysis allows modification of aromatic side chains that is selective for coil structures and creates the first selective chemical modification of the phenylalanine residue.
Metallopeptides for asymmetric dirhodium catalysis.
- Ramya Sambasivan, Z. Ball
- Chemistry, BiologyJournal of the American Chemical Society
- 14 July 2010
Analysis of the library indicates that the i-1 and i+3 positions of nonapeptides have the most significant effect on enantioselectivity, though the structural basis for selectivity is different at each of the positions.
Sequence-specific inhibition of a designed metallopeptide catalyst.
It is demonstrated that designed metallopeptide catalysts can be inhibited in a sequence-specific manner, mimicking the inhibition and regulation of natural enzymes.
Atovaquone is active against AML by upregulating the integrated stress pathway and suppressing oxidative phosphorylation.
- A. Stevens, Michael Xiang, D. Frank
- Medicine, BiologyBlood Advances
- 19 December 2019
Insight is provided into the complex biological effects of atovaquone, highlighting its potential as an anticancer therapy with novel and diverse mechanisms of action, and support further clinical evaluation of atOVAquone for pediatric and adult AML.
Programming Post-Translational Control over the Metabolic Labeling of Cellular Proteins with a Noncanonical Amino Acid.
- E. E. Thomas, Naresh Pandey, Sarah E Knudsen, Z. Ball, J. Silberg
- BiologyACS Synthetic Biology
- 17 May 2017
Findings suggest that split MetRS can be fused to a range of ligand-binding proteins to create aaRSs whose metabolic labeling activities depend upon post-translational interactions with ligands.
Rhodium-catalyzed cysteine modification with diazo reagents.
- Rituparna Kundu, Z. Ball
- Chemistry, BiologyChemical Communications
- 19 April 2013
A simple rhodium(II) complex catalyzes cysteine modification with diazo reagents and the resulting linkage is significantly more stable in human plasma serum, when compared to common maleimide reagents.
Well-Defined Fullerene-Containing Homopolymers and Diblock Copolymers with High Fullerene Content and Their Use for Solution-Phase and Bulk Organization
- Z. Ball, K. Sivula, J. Fréchet
- Chemistry, Materials Science
A fullerene-containing norbornene derivative is used for ring-opening metathesis polymerization to synthesize living polymers with high fullerene content. Incorporation of fullerene at every repeat…
Ascorbate as a pro-oxidant: mild N-terminal modification with vinylboronic acids.
This mild and selective aqueous reactivity enables selective single-modification of the B chain of human insulin with vinylboronate reagents.