Z Rotkiewicz

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Twenty serial passages of the TK900 strain of Aujeszky's disease virus (ADV) and the Roakin strain of Newcastle disease virus (NDV) were made in a chicken embryo cell culture (CECC), in the presence of two antiviral agents: Methisoprinol and KLP-602. The physicochemical properties of passaged viruses were determined. The results obtained suggest that(More)
An amyloidosis was induced in dwarf pigs by intramuscular injections of casein sodium. Six months' administration of the preparation (3 times a week) in a dosis of 0.5 grammes per injection was the most effective. Histologically amyloid deposits were found in almost all the internal organs, particularly in the mucous membranes of the digestive and the(More)
The effect of Methisoprinol (active substance: isoprinozine) on the replication of two animal viruses, the TK900 strain of Aujeszky's disease virus and the Roakin strain of the Newcastle disease virus was investigated. When the maximal tolerable doses of the drug were added to two cell cultures (CECC and GMK), its effect on the level of infectious titres of(More)
The aim of the present study was to examine the effects of two immunomodulators (KLP-602 and Methisoprinol) on the proliferation of two strains of Newcastle disease virus in chick embryos. The effect of the maximum tolerable doses of both drugs (Methisoprinol--6 mg/embryo, KLP-602--5 mg/embryo) on lymphocyte reactivity were determined prior to the(More)
The effect of KLP-602 (active substance: lysozyme dimer) on the replication of two animal viruses: the TK900 strain of Aujeszky's disease virus and the Roakin strain of the Newcastle disease virus were investigated. The maximal tolerable dose of the drug was determined for two cell cultures (CECC and GMK) and the effect of the medicine on the titre range of(More)
The immunostimulating effect of Methisoprinol and KLP-602 on the development of organs of the immunological system, the reactivity of lymphocytes and selected biochemical parameters of allantoic fluid (the activity of ceruloplasmin and lysozyme) during embryogenesis was tested. A positive effect of these drugs, especially KLP-602, was found. KLP-602(More)
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