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BACKGROUND Sonographic and biochemical methods for Down's syndrome screening have developed simultaneously, but independently. As a consequence, the rate of invasive procedures for fetal karyotyping has dramatically increased and become an important public health issue which needs to be controlled. One approach is to combine sonographic and biochemical(More)
OBJECTIVE To compare the efficacy and safety of vaginal misoprostol (50 microg) with vaginal dinoprostone. DESIGN Double-blind randomised trial. SETTING Obstetrics Department, Poissy Hospital, France. PARTICIPANTS 370 patients with medical indications for induction of labour. OUTCOME MEASURES Vaginal deliveries within 24 hours, as well as time to(More)
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