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E-cadherin (CDH1) is a tumor suppressor involved in epithelial cell-cell interactions. Single nucleotide polymorphisms (SNP) in the CDH1 gene, -160C/A and -347G/GA in the 5'-promoter region and +54C/T in the 3'-untranslated region (UTR) have been shown to be associated with tumor development and progression via modifying transcriptional activity, mRNA(More)
P73, a p53 homolog, has some p53-like activities and plays an important role in modulating cell cycle, apoptosis and DNA repair. The two linked polymorphisms in the non-coding region of exon2 of p73 gene, named G4C14-A4T14, may alter translation efficiency of the gene. The transcription of p73 gene is initiated by three promoters, termed P1-P3. There is a(More)
OBJECTIVE To survey concentrations and time-variability of the major anions of human saliva using ion chromatography (IC). MATERIALS AND METHODS Resting saliva samples after overnight fasting, obtained under standardized conditions in time-series for 10 subjects, were analysed for chloride, phosphate, nitrate, sulphate, thiocyanate, acetate and lactate. A(More)
OBJECTIVE To use solid titration and laser-scattering end-point detection to determine the hydroxyapatite (HAP) solubility isotherm at 37 degrees C in a plain KCl solution, with CO(2) present, and with additional phosphate. DESIGN Pulverised HAP solid was used to perform a titration to saturation. A very sensitive detector capable of detecting the light(More)
OBJECTIVE Vascular endothelial growth factor (VEGF) is the most potent inducer of neovasculature, and its increased expression has been related to a worse clinical outcome in many disease. Angiogenesis from thyroid cancer cell plays the important roles in post-surgical persistent, recurrent, and metastatic papillary thyroid cancer (PTC). Vascular(More)
OBJECTIVE Assess the applicability of ion chromatography (IC) for human saliva studies. MATERIALS AND METHODS The behaviour of an ion chromatograph (DX-100, Dionex) in the analysis of human saliva was examined in the following respects: calibration, reproducibility, recovery, and effect of pre-treatment conditions (dilution, temperature). The eluents used(More)
Different size InGaN/GaN based micro-LEDs (μLEDs) are fabricated. An extremely high injection level above 16 kA/cm2 is achieved for 10 μm-diameter LED. The lateral current density and carrier distributions of the μLEDs are simulated by APSYS software. Streak camera time resolved photoluminescence (TRPL) results show clear evidence that the band-gap(More)