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We present two experiments demonstrating that: (i) the latency of perception of the position of a small visual target moving towards the fovea is shorter than that of the same target moving away from the fovea; (ii) the reaction time (RT) to onset of motion of the same type of target is also shorter when it moves towards the fovea; and (iii) the RT to onset(More)
EEG changes induced by intraperitoneal injection of 6 mg/kg atropine sulphate were studied in freely moving rats with implanted electrodes. Sleep-like high voltage slow wave activity appeared in neocortex, hippocampus and reticular formation attaining maximum approximately 20 minutes after atropine injection. At the height of the atropine effect one-trial(More)
The effect of physostigmine on EEG activity and conditioning was studied in rats. Theta activity develops in the hippocampus of curarized or freely moving unanesthetized animals 3–7 min after i.p. injection of 1 mg/kg physostigmine salicylate, attains maximum after 10 min and disappears after 30–60 min. Gradual impairment of learning corresponds to the(More)
The effects of scopolamine hydrobromide and its quaternary analogue, scopolamiae methylbromide, in two doses (0.2 and 0.4 mg/kg) upon delayed matching performance was studied in monkeys. Scopolamine in the lower dose depressed significantly only performance rate, while in the higher dose it depressed both performance rate and percentage accuracy of the(More)
In freely moving rats with implanted electrodes the influence of subcutaneously administered atropine sulphate on EEG signs of sleep cycles was analysed. Four subsequent single doses of 0.75; 1.0; 1.25; 2.25 or 3.0 mg/kg of atropine repeated in 30 min intervals were applied, the total doses being 3.0; 4.0; 5.0; 9.0 resp. 12 mg/kg. Even after high doses of(More)
A small acute brain puncture produced retrograde amnesia in a passive avoidance learning situation in mice. If injury to the hippocampus was inflicted either immediately, 1 hour after the learning, or 1 hour before the learning, the animals showed a retention deficit; the degree of this deficit was related to the time interval. No effect of this injury was(More)