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Naphthalen-1-yl-(4-pentyloxynaphthalen-1-yl)methanone: a potent, orally bioavailable human CB1/CB2 dual agonist with antihyperalgesic properties and restricted central nervous system penetration.

• Edward K. Dziadulewicz, Stuart Bevan, +22 authors Jiri Zadrobilek
• Journal of medicinal chemistry
• 2007

Selective activation of peripheral cannabinoid CB1 receptors has the potential to become a valuable therapy for chronic pain conditions as long as central nervous system effects are attenuated. A new… (More)

Increased first-trimester nuchal translucency as a prenatal manifestation of salt-wasting congenital adrenal hyperplasia.

• Jack Fincham, Pranav P Pandya, Bulend Yuksel, Yvonne Loong, Jatin P Shah
• Ultrasound in obstetrics & gynecology : the…
• 2002

Congenital adrenal hyperplasia (CAH) is an autosomal recessive disorder that results from a deficiency in one or other of the five enzymes of cortisol biosynthesis. The most common form of CAH is… (More)

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