Yvonne Bayer

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The purpose of this review is to summarize current knowledge of the etiology of euthyroid and toxic multinodular goiter (MNG) with respect to the epidemiology, clinical characteristics, and molecular pathology. In reconstructing the line of events from early thyroid hyperplasia to MNG we will argue the predominant neoplastic character of nodular structures,(More)
BACKGROUND In medicine, the use of standard operating procedures (SOPs) is often evaluated using questionnaires (QUES). However, QUES can have limitations with regard to method, thus leading to errors. Simulation (SIM) offers another opportunity for evaluation. We hypothesized that medical errors in the evaluation of SOPs using QUES could be detected by(More)
Euthyroid goiter is characterized by diffuse or nodular enlargement of the thyroid gland. Iodine deficiency and cigarette smoking have been identified as important environmental factors. However, family and twin pair studies suggest a strong genetic predisposition. Therefore, we performed the first extended genome-wide scan to identify susceptibility loci(More)
BACKGROUND Analysis of critical incidents in anaesthesia practice emphasizes the important role of non-technical skills (NTS) in improving patient safety. Therefore, debriefing with regard to NTS has been added to medical management (MM) simulator training to improve acute crisis competencies of anaesthesiologists. The purpose of this study was to compare(More)
This study is a prospective assessment of a joint operation to repair concomitant genital and rectal prolapse, including 10 women treated for concomitant genital and rectal prolapse from 1991 to 1995. Joel-Cohen vaginal hysterectomy was used to correct the genital prolapse, followed by the Altemeier procedure (transperineal rectosigmoidectomy) to correct(More)
Iodine deficiency is the most important etiological factor for euthyroid endemic goiter. However, family and twin pair studies also strongly indicate a genetic prediposition. In euthyroid goiters molecular defects in the thyroglobulin (TG), and Na+/I− symporter (NIS) gene have been identified. Numerous mutations in the Pendrin (PDS) gene have been found in(More)
BACKGROUND Cutoff filters may improve contrast sensitivity in different retinal dystrophies and therefore lead to improved visual function. We investigated whether cutoff filters result in improved reading ability in age-related macular degeneration (AMD). METHODS Reading performance was examined in 22 patients with AMD aged 63-91 years (visual acuity(More)
Splenosis consists of the autotransplantation of splenic tissue following splenic trauma. Unlike hypersplenism, to which it is not related, it does not usually result in any clinical manifestation. It is usually discovered incidentally during operation years after splenic trauma. A benign tumor is found which may or may not be histologically identical with(More)
Die Bestimmung der Sehschärfe bei sehbehinderten Kindern oder bei Mehrfachbehinderten ist schwierig. In unserer Sehbehindertensprechstunde haben wir ein Testverfahren eingesetzt, bei dem Würfel unterschiedlicher Größe und Farbe als Objekte präsentiert werden, um daraus die Sehschärfe zu schätzen. Ziel dieser Arbeit war der Vergleich der anhand dieses(More)