Yvonne Bader

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BACKGROUND Pancreatic cancer constitutes an entity which is difficult to treat and, therefore, mostly fatal. Since heavy water (deuterium oxide, D2O) was shown to be active in various cancer cell lines in vitro and in vivo, we now investigated its effects in human pancreatic tumor cells. MATERIALS AND METHODS The cytotoxic effects of D2O were examined in(More)
OBJECTIVE To investigate a possible correlation between the volume of the tubal ectopic pregnancy (EP) measured by vaginal-ultrasound (VUS) and methotrexate (MTX) therapy outcome. STUDY DESIGN Data of EP volume measured by one expert-sonographer, viability, clinical symptoms, previous IVF/insemination, follow-up of β-hCG and progesterone levels, and(More)
OBJECTIVE To determine the optimal serum β-hCG cut-off level to predict MTX treatment success in tubal ectopic pregnancy (EP). STUDY DESIGN Data of 240 women, who presented between 2003 and 2011 at the Department of Gynecology and Obstetrics, Medical University of Vienna, with tubal EP and who received MTX as primary treatment, were retrieved from the(More)
ErbB2 overexpressing breast tumors have a poor prognosis and a high risk to develop chemoresistance to therapeutic treatment. "Chemoresistance" is a response of cells to toxic stress, and, although it is a common phenomenon, it is still poorly defined. However, a detailed understanding is required to target desensitized pathways and mechanisms for(More)
The development of chemoresistant breast cancer is poorly understood and second treatment options are barely investigated. The term 'chemoresistance' is ill-defined and thus, our experimental analyses aimed to disentangle the resistance to cell cycle arrest from the resistance to trigger apoptosis, both of which are important mechanisms to be targeted by(More)
To present a successful case of in vitro fertilization (IVF) and single embryo transfer (SET) in a kidney transplant (NTX) patient and review of the literature. Case report and review of the literature. IVF-Unit in a university medical center. A 31 year-old nulliparous woman with primary infertility and a history of two kidney transplants. IVF-SET Live(More)
Chemoresistance is a biological response of cells to survive toxic stress. During cancer treatment the development of chemoresistance is a major problem. The mechanisms how cells become insensitive, and which downstream pathways are affected are not completely understood. Since it has not been well analysed which and how many regulative disorders are(More)
Accurate timing of interventions during the gait cycle are critical for optimal efficacy of assistive devices, e.g., to reduce the metabolic cost of walking. However, timing control generally relies on methods that can neither account for changes in the stride duration over time due to different walking speeds, nor reject isolated abnormal strides, which(More)
OBJECTIVE Transplantation results in a 5-time elevated risk for a variety of malignancies (Kaposi sarcoma, skin, liver, lung, gastrointestinal cancer). A patient's risk for malignancies could be of particular interest for the follow-up programs of patients and risk adaption after kidney transplantation. The aim of this study was to identify independent risk(More)
The radiation-biological effects of resveratrol (Res) alone or with mitomycin C (MMC) were investigated under various conditions in human breast cancer cells (MCF-7). The data of the survival curves obtained in aerated media (acting species: 42% OH, 54% 02*-) showed that Res possesses antitumor activity and also acts as an efficient radical scavenger. This(More)