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- Chad Myskiw, Janilyn Arsenio, Rebekah van Bruggen, Yvon Deschambault, Jingxin Cao
- Journal of virology
- 2009
The vaccinia virus double-stranded RNA binding protein E3 has been demonstrated to inhibit the expression of cytokines, including beta interferon (IFN-beta) and tumor necrosis factor alpha… (More)
- Chad Myskiw, Janilyn Arsenio, +5 authors Jingxin Cao
- Journal of virology
- 2011
Poxviruses are important human and animal pathogens that have evolved elaborate strategies for antagonizing host innate and adaptive immunity. The E3 protein of vaccinia virus, the prototypic member… (More)
- Chad Myskiw, Yvon Deschambault, Kristel Jefferies, RunTao He, Jingxin Cao
- Journal of virology
- 2007
Aurintricarboxylic acid (ATA) has been shown to inhibit the replication of viruses from several different families, including human immunodeficiency virus, vesicular stomatitis virus, and the… (More)
- Chad Myskiw, Janilyn Arsenio, +4 authors Jingxin Cao
- Virology
- 2011
RNA species produced during virus replication are pathogen-associated molecular patterns (PAMPs) triggering cellular innate immune responses including induction of type I interferon expression and… (More)
- Kevin J Dueck, YuanShen Sandy Hu, +4 authors Jingxin Cao
- Journal of virology
- 2015
UNLABELLED
Vaccinia E3 protein has the biochemical capacity of binding to double-stranded RNA (dsRNA). The best characterized biological functions of the E3 protein include its host range function,… (More)
- P Guillaume Poliquin, Florian Vogt, +9 authors James E. Strong
- The Journal of infectious diseases
- 2016
BACKGROUND
Ebola viruses (EBOVs) are primarily transmitted by contact with infected body fluids. Ebola treatment centers (ETCs) contain areas that are exposed to body fluids through the care of… (More)
- Janilyn Arsenio, Yvon Deschambault, Jingxin Cao
- Virology
- 2008
The E3L protein of vaccinia virus (VV) is well known for its capacity to evade cellular innate antiviral immunity related to interferon (IFN), for example PKR and RNaseL mediated antiviral… (More)
- Guillaume Poliquin, Duane J. Funk, +59 authors James E. Strong
- Intensive Care Medicine Experimental
- 2019
BackgroundThere are currently limited data for the use of specific antiviral therapies for the treatment of Ebola virus disease (EVD). While there is anecdotal evidence that supportive care may be… (More)
- Marsha S. Russell, Abenaya Muralidharan, +5 authors Xuguang Li
- PloS one
- 2018
Cotton rats are an important animal model to study infectious diseases. They have demonstrated higher susceptibility to a wider variety of human pathogens than other rodents and are also the animal… (More)
- Derek R. Stein, Patrycja Sroga, Bryce M Warner, Yvon Deschambault, Guillaume Poliquin, David Safronetz
- Emerging infectious diseases
- 2019
Use of the vesicular stomatitis virus (VSV)-based Ebola virus vaccine during outbreaks and the potential use of a similar VSV-based Lassa virus vaccine has raised questions about the vaccines'… (More)