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PURPOSE Hypoxia-selective cytotoxic agents, like tirapazamine (TPZ), must diffuse considerable distances in tumors to reach their target cell population. This study uses a new three-dimensional tissue culture model, in which cells are grown as multicellular layers (MCL), to investigate whether metabolic consumption of TPZ is sufficiently rapid to compromise(More)
The inclusive e + p single and double differential cross sections for neutral and charged current processes are measured with the H1 detector at HERA. The data were taken in 1999 and 2000 at a centre-of-mass energy of √ s = 319 GeV and correspond to an integrated luminosity of 65.2 pb −1. The cross sections are measured in the range of four-momentum(More)
Cross sections for the production of two isolated muons up to high di-muon masses are measured in ep collisions at HERA with the H1 detector in a data sample corresponding to an integrated luminosity of 71 pb −1 at a centre of mass energy of √ s = 319 GeV. The results are in good agreement with Standard Model predictions, the dominant process being(More)
Results are presented on the photoproduction of isolated prompt photons, inclusively and associated with jets, in the γp center of mass energy range 142 < W < 266 GeV. The cross sections are measured for the transverse momentum range of the photons 5 < E γ T < 10 GeV and for associated jets with E jet T > 4.5 GeV. They are measured differentially as a(More)
A search for single top quark production is performed in e ± p collisions at HERA. The search exploits data corresponding to an integrated luminosity of 118.3 pb −1. A model for the anomalous production of top quarks in a flavour changing neutral current process involving a tuγ coupling is investigated. Decays of top quarks into a b quark and a W boson are(More)
A measurement is presented of dijet and 3-jet cross sections in low-Ø diffractive deep-inelastic scattering interactions of the type Ô , where the system is separated by a large rapidity gap from a low-mass baryonic system. Data taken with the H1 detector at HERA, corresponding to an integrated luminosity of ½½¼ ÔÔ ½ , are used to measure hadron level(More)
The HERA collider has recently been upgraded to produce a factor of approximately 5 more luminosity. In parallel, upgrades to the H1 detector and trigger have been necessary. One of the projects was the design of an improved Fast Track Trigger (FTT) which should replace the old track trigger and is based on the central drift chambers of the H1 experiment.(More)
Deep-inelastic positron-proton interactions at low values of Bjorken-x down to x ≈ 4 · 10 −5 which give rise to high transverse momentum π •-mesons are studied with the H1 experiment at HERA. The inclusive cross section for π •-mesons produced at small angles with respect to the proton remnant (the forward region) is presented as a function of the(More)
A search for scalar top quarks in R–parity violating supersymmetry is performed in e + p collisions at HERA using the H1 detector. The data, taken at √ s = 319 GeV and 301 GeV, correspond to an integrated luminosity of 106 pb −1. The resonant production of scalar top quarks˜t in positron quark fusion via an R–parity violating Yukawa coupling λ is considered(More)