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We identified an NH2-terminally truncated HER-2/neu product of M(r) 95,000 with in vitro kinase activity by Western blotting and immunoprecipitations using domain-specific antibodies. p95 levels correlated with the extracellular domain (ECD) shed from different cells under varied conditions. Both ECD and p95 were at approximately 20-fold lower levels in(More)
This paper presents the design, implementation and evaluation of a context-aware recommendation system that promotes the adoption of a healthy and active lifestyle. A Smartphone application that provides personalized and contextualized advice based on geo information, weather, user location and agenda was developed and evaluated by a user study. The results(More)
This paper presents the practices of a research aiming at the design of a context-aware recommendation system that promotes the adoption of a healthy and active lifestyle. A Smartphone application that provides personalized and contextualized advice on physical activities was developed. The goal of our endeavor is to find out whether this recommendation(More)
Enhanced levels of disulfide-linked dimers of the neu oncogene product have been suggested to be associated with the transformed state [Weiner DB, Liu J, Cohen JA, Williams WV, Greene MI: Nature 338:230-231, (1989)]. We, therefore, investigated the properties of the dimeric forms of p185HER-2/neu from the human breast carcinoma cell line, SK-BR-3. We found(More)
We identified an MI ,-U>rmm;ill> truncated HER-2/neu product of M, 95,000 with in vitro kinase activity by Western blotting and immunoprecipitations using domain-specific antibodies. p95 levels correlated with the extracellular domain (ECD) shed from different cells under varied con ditions. Both ECD and p95 were at -20-fold lower levels in SKOV3 ovarian(More)
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