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A T-mesh is basically a rectangular grid that allows T-junctions. In this paper, we propose a method based on Bézier nets to calculate the dimension of a spline function space over a T-mesh. When the order of the smoothness is less than half of the degree of the spline functions, a dimension formula is derived which involves only the topological quantities(More)
Gaucher disease (GD) is a common lysosomal storage disorder caused by the deficiency of acid β-glucosidase, due to mutations in the GBA gene. To explore the clinical and molecular characteristics of GD patients from Southern China, GBA gene were analyzed by nest PCR and direct Sanger-sequencing. Novel missense mutations were transiently transfected in COS-7(More)
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