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Crosstalk of autophagy and apoptosis: Involvement of the dual role of autophagy under ER stress
Endoplasmic reticulum (ER) stress is a common cellular stress response that is triggered by a variety of conditions that disturb cellular homeostasis, and induces cell apoptosis. Autophagy, anExpand
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ROS and Autophagy: Interactions and Molecular Regulatory Mechanisms
Abstract Reactive oxygen species (ROS) and antioxidant ingredients are a series of crucial signaling molecules in oxidative stress response. Under some pathological conditions such as traumatic brainExpand
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Crosstalk of ER stress‐mediated autophagy and ER‐phagy: Involvement of UPR and the core autophagy machinery
Endoplasmic reticulum (ER) stress, a common cellular stress response, is closely related to the activation of autophagy that is an important and evolutionarily conserved mechanism for maintainingExpand
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The dual role of autophagy under hypoxia-involvement of interaction between autophagy and apoptosis
Abstract Hypoxia is one of severe cellular stress and it is well known to be associated with a worse outcome since a lack of oxygen accelerates the induction of apoptosis. Autophagy, an important andExpand
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Effect of CPAP therapy on liver disease in patients with OSA: a review
Obstructive sleep apnea (OSA) may play an important role in the progression of nonalcoholic fatty liver disease (NAFLD).The effect of continuous positive airway pressure (CPAP) treatment, theExpand
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Effect of different levels of intermittent hypoxia on autophagy of hippocampal neurons
PurposeThe current study was carried out to assess the effects of different levels of intermittent hypoxia (IH) on autophagy in hippocampal neurons, and explore the extent, frequency and duration ofExpand
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Potential role of exosomes in the pathophysiology, diagnosis, and treatment of hypoxic diseases.
Exosomes are extracellular vesicles that originate in the endosomal system. They perform important functions for cell-to-cell communication by transferring bioactive cargoes to recipient cells orExpand
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  • Open Access
Sirt1: Role Under the Condition of Ischemia/Hypoxia
Silent information regulator factor 2-related enzyme 1 (sirtuin 1, Sirt1) is a nicotinamide adenine dinucleotide-dependent deacetylase, which can deacetylate histone and non-histone proteins andExpand
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Role of Ca²⁺ and ion channels in the regulation of apoptosis under hypoxia.
Hypoxia is a kind of common pathological condition existing in various diseases such as sleep apnea syndrome, myocardial infarction and stroke, which can precipitate the onset of diseases throughExpand
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Autophagy activation promotes removal of damaged mitochondria and protects against renal tubular injury induced by albumin overload.
Proteinuria (albuminuria) is an important cause of aggravating tubulointerstitial injury. Previous studies have shown that autophagy activation can alleviate renal tubular epithelial cell injuryExpand
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