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Prevalence and genetic characterization of Cryptosporidium, Enterocytozoon, Giardia and Cyclospora in diarrheal outpatients in china
TLDR
Data indicated that C. andersoni is the fourth major Cryptosporidium species infecting humans in addition to C. hominis, C. parvum and C. meleagridis, and patients infected with Cryptospora and Enterocytozoon bieneusi had higher infection rates in winter than in spring in this area. Expand
The identification of the Cryptosporidium ubiquitum in pre-weaned Ovines from Aba Tibetan and Qiang autonomous prefecture in China.
TLDR
It is suggested that the high incidence of Cryptosporidium in sheep poses a significant public health threat and that surveillance practices must be established to prevent zoonotic disease of humans. Expand
Impairment of dendritic cell function and induction of CD4+CD25+Foxp3+ T cells by excretory-secretory products: a potential mechanism of immune evasion adopted by Echinococcus granulosus
TLDR
It is concluded that ES of adult E. granulosus inhibited DC function, impaired the development of Th1 cells induced by CpG, and induced CD4+CD25+Foxp3+ regulatory T cells in an IL-10-independent manner. Expand
Prevalence of the Cryptosporidium Pig Genotype II in Pigs from the Yangtze River Delta, China
TLDR
The finding of Cryptosporidium pig genotype II in pigs in the Yangtze River delta area suggests that pig farms in this region must be considered a public health threat and proper control measures be introduced. Expand
Transcriptome Profiles of the Protoscoleces of Echinococcus granulosus Reveal that Excretory-Secretory Products Are Essential to Metabolic Adaptation
TLDR
This study uses Roche 454 sequencing technology and in silico secretome analysis to explore the transcriptome profiles of the PSCs from E. granulosus and elucidate the potential functions of the excretory-secretory proteins (ESPs) released by the parasite. Expand
De novo assembly and transcriptome characterization: novel insights into the natural resistance mechanisms of Microtus fortis against Schistosoma japonicum
TLDR
Gene ontology terms and pathways related to the DEGs revealed that up-regulated transcripts were involved in metabolism, immunity and inflammatory responses, and demonstrated that natural and adaptive immune responses, play an important role in M. fortis immunity to S. japonicum. Expand
Recruitment of Neutrophils Mediated by Vγ2 γδ T Cells Deteriorates Liver Fibrosis Induced by Schistosoma japonicum Infection in C57BL/6 Mice
TLDR
It is suggested that during S. japonicum infection, Vγ2 T cells can recruit neutrophils and aggravate liver fibrosis by secreting IL-17A, the first report that a subset of γδ T cells plays a partial role in the pathological process of schistosome infection. Expand
Toll-like receptor-2 regulates macrophage polarization induced by excretory-secretory antigens from Schistosoma japonicum eggs and promotes liver pathology in murine schistosomiasis
TLDR
A novel role for M2b polarization in the pathogenesis of schistosome infection is revealed and the size of granuloma and the severity of the fibrosis in the livers of TLR2-/- mice were significantly reduced compared to that in WT mice. Expand
The formation of egg granulomas in the spleens of mice with late Schistosoma japonicum infection alters splenic morphology
TLDR
It is found that eggs deposition in the spleens of infected mice occurred frequently but only occasionally led to granulomas formation, highlighting that lymphoid follicles can change the local immune environment and lead to changes in the splenic morphology of mice with chronic schistosomiasis. Expand
High throughput data analyses of the immune characteristics of Microtus fortis infected with Schistosoma japonicum
TLDR
Elevated expression of metabolites and pathways involved in histidine metabolism, valine, leucine, and isoleucine biosyntheses, and lysine degradation may promote the phagocytic function of the neutrophils and natural killer cell activity following TLR activation. Expand
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