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Non-esterified fatty acids (NEFAs) are important induction factors of inflammatory responses in some metabolic diseases. High plasma levels of NEFAs and oxidative stress exist in the dairy cows with ketosis. The aim of this study was to investigate whether high levels of NEFAs can induce inflammatory response and the specific molecular mechanism in the(More)
A high plasma concentration of non-esterified fatty acids (NEFAs) is an important pathogenic factor that leads to ketosis and fatty liver in dairy cows. NEFAs may be associated with oxidative stress in dairy cows with ketosis or fatty liver and the subsequent induction of hepatocyte damage. However, the molecular mechanism of NEFAs-induced oxidative stress(More)
Zinc deficiency impairs the hepatic lipid metabolism. Previous studies were focused on the negative effects of zinc deficiency on the hepatic lipid metabolism. A few studies investigated the effects of high zinc levels on the lipid metabolism in hepatocytes. In this study, rat hepatocytes were cultured and treated with different and high concentrations of(More)
A renvoyer à l'Ecole Doctorale par voie électronique au plus tard le 03 avril 2015 ed419.biosigne@u-psud.fr Cet appel constitue la 1 ère phase obligatoire avant toute candidature éventuelle au concours de l'ED (2 ème phase juin 2015) – Concours ED : 02 et 03 juillet 2015 This call is the first mandatory step before applying to participate in the competitive(More)
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