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Cecropin P1 was first identified as a mammalian antimicrobial peptide isolated from the pig intestine. Much research aimed at characterizing this peptide has been reported. Recently, the workers who discovered the peptide corrected their original conclusion, and confirmed that this peptide originates in fact from the pig intestinal parasitic nematode,(More)
The site-selective nuclear spin-lattice relaxation rate T −1 1 is theoretically studied inside a vortex core in a chiral p-wave superconductor within the framework of the quasiclassical theory of superconductivity. It is found that T −1 1 at the vortex center depends on the sense of the chirality relative to the sense of the magnetic field. Our numerical(More)
An elementary theory is presented for solving the Sutherland model with arbitrary internal symmetry such as SU(ν) or a supersymmetry SU(ν, µ). The ground-state wave function and all the energy levels are derived. One starts with solving a variant of the model with distinguishable particles, and then (anti)symmetrizes the solution. The theory is also applied(More)
Dynein ATPases power diverse microtubule-based motilities. Each dynein motor domain comprises a ring-like head containing six AAA+ modules and N- and C-terminal regions, together with a stalk that binds microtubules. How these subdomains are arranged and generate force remains poorly understood. Here, using electron microscopy and image processing of tagged(More)
Two genes encoding the ASABF (Ascaris suum antibacterial factor)-type antimicrobial peptide, abf-1 and abf-2, were identified in Caenorhabditis elegans. Recombinant ABF-2 exhibited potent microbicidal activity against Gram-positive and Gram-negative bacteria, and yeasts. The tissue-specific distribution estimated by immunofluorescence staining and(More)
When should service staff initiate interaction with a visitor? Neither simply-proactive (e.g. talk to everyone in a sight) nor passive (e.g. wait until being talked to) strategies are desired. This paper reports our modeling of polite approaching behavior. In a shopping mall, there are service staff members who politely approach visitors who need help. Our(More)
BACKGROUND The ability of staphylococci to grow in a wide range of salt concentrations is well documented. In this study, we aimed to clarify the role of cardiolipin (CL) in the adaptation of Staphylococcus aureus to high salinity. RESULTS Using an improved extraction method, the analysis of phospholipid composition suggested that CL levels increased(More)
The yellow variegated2 (var2) mutant in Arabidopsis thaliana has been studied as a typical leaf-variegated mutant whose defect results from the lack of FtsH2 metalloprotease in chloroplasts. The var2 green sectors suffer from photo-oxidative stress and accumulate high levels of reactive oxygen species (ROS) because of compromised Photosystem II repair. This(More)
BACKGROUND NP4P is a synthetic peptide derived from a natural, non-antimicrobial peptide fragment (pro-region of nematode cecropin P4) by substitution of all acidic amino acid residues with amides (i.e., Glu --> Gln, and Asp --> Asn). RESULTS In the presence of NP4P, some membrane-disrupting antimicrobial peptides (ASABF-alpha, polymyxin B, and nisin)(More)
BACKGROUND Cationic antimicrobial peptides (CAMPs) are well recognized to be promising as novel antimicrobial and antitumor agents. To obtain novel skeletons of CAMPs, we propose a simple strategy using acid-amide substitution (i.e. Glu→Gln, Asp→Asn) to confer net positive charge to natural non-antimicrobial sequences that have structures distinct from(More)