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Many clinically useful pharmaceuticals are semi-synthesized from natural products produced by actinobacteria and fungi. The synthetic protocols usually contain many complicated reaction steps and thereby result in low yields and high costs. It is therefore important to breed microorganisms that produce a compound most suitable for chemical synthesis. For a(More)
INTRODUCTION Although several etiopathogenetic mechanisms have been proposed, the causes of left ventricular apical ballooning syndrome are still controversial. CASE PRESENTATION A 51-year-old Japanese woman consulted the emergency room complaining of the sudden onset of anterior chest pain while shopping. We initially suspected her disease as left(More)
Background The increase in the number of elderly people results in the exponential increase of cancer incidence, though we are wondering how that of ATL change. We assessed the therapy and outcome of newly diagnosed or referred 66 ATL patients from 2006 to 2009. Serum of patient was preserved in freezer to detect soluble proteins, sCD30 and sIL-2R, using(More)
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