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Characterization of SoxB2 and SoxC genes in amphioxus (Branchiostoma belcheri): Implications for their evolutionary conservation

• Yushuang Lin, Dongyan Chen, Qiusheng Fan, Hongwei Zhang
• Science in China Series C: Life Sciences
• 2009

Most Sox genes directly affect cell fate determination and differentiation. In this study, we isolated two Sox genes: SoxB2 and SoxC from amphioxus (Branchiostoma belcheri), the closest living… (More)

Ptc, Smo, Sufu, and the Hedgehog signaling pathway in amphioxus.

• Yushuang Lin, Zhaoping Cai, +6 authors Hongwei Zhang
• Evolution & development
• 2009

The Hedgehog (Hh) signaling pathway regulates many developmental processes both in vertebrates and in invertebrates. However, little is known about this pathway in the cephalochordate amphioxus. In… (More)

Correction: GSK-3 Activity Is Critical for the Orientation of the Cortical Microtubules and the Dorsoventral Axis Determination in Zebrafish Embryos

• Ming Shao, Yushuang Lin, +4 authors Hongwei Zhang
• 2012

Characterization and expression of two amphioxus DDAH genes originating from an amphioxus-specific gene duplication.

• Dongyan Chen, Yushuang Lin, Hongwei Zhang
• Gene
• 2008

Two dimethylarginine dimethylaminohydrolase (DDAH) homologous genes in amphioxus are identified and cloned. The phylogenetic analysis indicates two DDAHs in amphioxus originated by independent… (More)

Characterization of AGAT, GAMT and CT1 in amphioxus: implications for the evolutionary conservation of creatine metabolism related molecules at the invertebrate-to-vertebrate transition

• Lifeng Wang, Dongyan Chen, Ying Zhang, Yushuang Lin, Jianwei Li, Hongwei Zhang
• Development Genes and Evolution
• 2008

In vertebrates, glycine amidinotransferase (AGAT), guanidinoacetate methyltransferase (GAMT), and creatine transporter (CT1) are three proteins involved in creatine synthesis. To provide insight into… (More)

Plasma Membrane Targeting of Protocadherin 15 Is Regulated by the Golgi-Associated Chaperone Protein PIST

• Hongyun Nie, Yueyue Liu, +5 authors Zhigang Xu
• Neural plasticity
• 2016

Protocadherin 15 (PCDH15) is a core component of hair cell tip-links and crucial for proper function of inner ear hair cells. Mutations of PCDH15 gene cause syndromic and nonsyndromic hearing loss.… (More)

Single nucleotide polymorphisms in the upstream regulatory region alter the expression of myostatin

• Wei Hu, Songyu Chen, Ran Zhang, Yushuang Lin
• In Vitro Cellular & Developmental Biology…
• 2013

The expression of the gene encoding myostatin (MSTN), the product of which is a negative regulator of skeletal muscle growth and development in mammals, is regulated by many cis-regulatory elements,… (More)

Developmental expression of amphioxus GABAA receptor-associated protein-like 2 gene

• Kailong Liang, Yushuang Lin, Yanjun Zhang, Zhongke Chen, Peijun Zhang, Hongwei Zhang
• Development Genes and Evolution
• 2004

A full-length amphioxus γ-aminobutyric acid type-A receptor-associated protein-like 2 (GABARAPL2) cDNA was isolated. Its sequence and developmental expression are first described in this paper. The… (More)

Characterization of the immune defense related tissues, cells, and genes in amphioxus

• Yushuang Lin, Dongyan Chen, +5 authors Hongwei Zhang
• Science China Life Sciences
• 2011

Amphioxus is an important animal model for phylogenetic analysis, including comparative immunology. Exploring the immune system in amphioxus contributes to our understanding of the origin and… (More)

Phylogenetic analysis and developmental expression of brp-like genes in amphioxus and zebrafish.

• Yushuang Lin, Xiaohui Zhang, Kailong Liang, Hui Yang, Hongwei Zhang
• Comparative biochemistry and physiology. Part B…
• 2005

The brp-like genes in amphioxus (Branchiostoma belcheri tsingtauense) and in zebrafish (Danio rerio) are reported. The putative brp-like proteins are orthologous to the ancestor of the human brain… (More)

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