Yushan Jiang

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It is believed that the stability and activity of client proteins are passively regulated by the Hsp90 (heat-shock protein 90) chaperone machinery, which is known to be modulated by its intrinsic ATPase activity, co-chaperones and post-translational modifications. However, it is unclear whether client proteins themselves participate in regulation of the(More)
Applying for information entropy theory, we present a measure of dependence for three-variable relationships: the three variables maximal information coefficient (3MIC). It is a kind of maximal information-based nonparametric exploration (MINE) statistics for identifying and classifying relationships in large data sets. 3MIC generalizes the Maximum(More)
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