In this paper, we evaluate the quality of zero bounds on the moduli of univariate complex polynomials. We select classical and recently developed bounds and evaluate their quality by using several sets of complex polynomials. As the quality of priori bounds has not been investigated thoroughly, our results can be useful to find optimal bounds to locate the… (More)
Although image-based phenotypic assays are considered a powerful tool for siRNA library screening, the reproducibility and biological implications of various image-based assays are not well-characterized in a systematic manner. Here, we compared the resolution of high throughput assays of image-based cell count and typical cell viability measures for cancer… (More)
Successfully automated sigmoidal curve fitting is highly challenging when applied to large data sets. In this paper, we describe a robust algorithm for fitting sigmoid dose-response curves by estimating four parameters (floor, window, shift, and slope), together with the detection of outliers. We propose two improvements over current methods for curve… (More)
In this paper, we investigate the performance of zero bounds due to Kalantari and Dehmer by using special classes of polynomials. Our findings are evidenced by numerical as well as analytical results.