Nathan Dascal2
Ida Rishal2
2Nathan Dascal
2Ida Rishal
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G protein-activated K(+) channels (GIRKs; Kir3) are activated by direct binding of Gbetagamma subunits released from heterotrimeric G proteins. In native tissues, only pertussis toxin-sensitive G proteins of the G(i/o) family, preferably Galpha(i3) and Galpha(i2), are donors of Gbetagamma for GIRK. How this specificity is achieved is not known. Here, using(More)
In this and the associated article BioBlender: A Software for Intuitive Representation of Surface Properties of Biomolecules [1], we present BioBlender as a complete instrument for the elaboration of motion (here) and the visualization [1] of proteins and other macromolecules, using instruments of computer graphics. A vast number of protein (if not most)(More)
Cardiac and neuronal G protein-activated K+ channels (GIRK; Kir3) open following the binding of Gbetagamma subunits, released from Gi/o proteins activated by neurotransmitters. GIRKs also possess basal activity contributing to the resting potential in neurons. It appears to depend largely on free Gbetagamma, but a Gbetagamma-independent component has also(More)
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