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AntEpiSeeker: detecting epistatic interactions for case-control studies using a two-stage ant colony optimization algorithm
We propose a new two-stage ant colony optimization algorithm for detecting epistasis in a case-control design. Expand
LSOSS: Detection of Cancer Outlier Differential Gene Expression
Detection of differential gene expression using microarray technology has received considerable interest in cancer research studies. Recently, many researchers discovered that oncogenes may beExpand
GEPS: the Gene Expression Pattern Scanner
Gene Expression Pattern Scanner is a web-based server to provide interactive pattern analysis of user-submitted microarray data for facilitating their further interpretation. Expand
Sample size determination for classifiers based on single-nucleotide polymorphisms.
Single-nucleotide polymorphisms (SNPs), believed to determine human differences, are widely used to predict risk of diseases. Typically, clinical samples are limited and/or the sampling cost is high.Expand
AntEpiSeeker2.0: extending epistasis detection to epistasis-associated pathway inference using ant colony optimization
Genome-wide association studies (GWAS) have become a standard method for finding genetic variations that contribute to common, complex diseases. Recently, it is suggested that these diseases may beExpand
Determination of sample size for a multi-class classifier based on single-nucleotide polymorphisms: a volume under the surface approach
We derive an optimal Bayes classifier and a linear classifier based on coded SNP data from D(≥2) classes, and obtain a normal approximation to the probability of correct classification for each classifier. Expand
Update of KDBI: Kinetic Data of Bio-molecular Interaction database
Kinetic Data of Bio-molecular Interaction database (KDBI) has been developed to provide information about experimentally determined kinetic data of protein–protein, protein–nucleic acid and protein–ligand interactions. Expand
A Comprehensive Analysis of Gene Expression Evolution Between Humans and Mice
Evolutionary changes in gene expression account for most phenotypic differences between species. Advances in microarray technology have made the systematic study of gene expression evolutionExpand
Finding the Sources of Missing Heritability within Rare Variants Through Simulation
Thousands of genome-wide association studies (GWAS) have been conducted to identify the genetic variants associated with complex disorders. However, only a small proportion of phenotypic variancesExpand
A computational framework for predicting obesity risk based on optimizing and integrating genetic risk score and gene expression profiles
Recent large-scale genome-wide association studies have identified tens of genetic loci robustly associated with Body Mass Index (BMI). Gene expression profiles were also found to be associated withExpand