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Discovery of a rich gene pool of bat SARS-related coronaviruses provides new insights into the origin of SARS coronavirus
TLDR
It is hypothesized that the direct progenitor of SARS-CoV may have originated after sequential recombination events between the precursors of these SARSr-CoVs, and highlights the necessity of preparedness for future emergence of Sars-like diseases.
Metagenomic Analysis of Viruses from Bat Fecal Samples Reveals Many Novel Viruses in Insectivorous Bats in China
TLDR
This study provides the first preliminary understanding of the virome of some bat populations in China, which may guide the discovery and isolation of novel viruses in the future.
Host Range, Prevalence, and Genetic Diversity of Adenoviruses in Bats
TLDR
The results support the notion, derived from previous studies based on RNA viruses, that bats seem to have the unusual ability to harbor a large number of genetically diverse viruses within a geographic location and/or within a taxonomic group.
Isolation and Characterization of a Novel Bat Coronavirus Closely Related to the Direct Progenitor of Severe Acute Respiratory Syndrome Coronavirus
TLDR
These results provide further evidence of the bat origin of the SARS-CoV and highlight the likelihood of future bat coronavirus emergence in humans.
Genetic diversity of novel circular ssDNA viruses in bats in China.
TLDR
Detailed analysis indicated that these sequences are distantly related to known circovirus/cyclovirus genomes and may represent 22 novel species that belong to the family Circoviridae.
Serological Evidence of Bat SARS-Related Coronavirus Infection in Humans, China
TLDR
This report developed a specific ELISA based on the nucleocapsid protein of a SARSr-CoV strain and detected its antibody in humans who are highly exposed to bat populations and demonstrated the Sarsr- CoV had spillover to humans, although did not cause clinical diseases.
Antibodies to Nipah or Nipah-like Viruses in Bats, China
TLDR
The detection of henipavirus antibody suggests that several bat species have been exposed to NiV or a closely related virus, and could be introduced into China by other susceptible bat species that overlap their habitat with pteropid bats in neighboring countries.
Characterization of a filovirus (Měnglà virus) from Rousettus bats in China
TLDR
The characterization of a phylogenetically distinct bat filovirus, named Měnglà virus (MLAV), whose genome shares 32–54% nucleotide sequence identity with known filoviruses, indicates a broad species cell tropism with a high risk of interspecies spillover transmission.
Serological evidence of ebolavirus infection in bats, China
TLDR
This study developed an enzyme linked immunosorbent assay (ELISA) for ebolavirus using the recombinant nucleocapsid protein and performed sero-surveillance for the virus among Chinese bat populations, revealing the presence of antibodies to ebolvirus in 32 of 843 bat sera samples.
Coexistence of multiple coronaviruses in several bat colonies in an abandoned mineshaft
TLDR
High frequency of infection by a diverse group of coronaviruses in different bat species in the mineshaft is found, and coronavirus co-infection was detected in all six bat species, highlighting the importance of bats as natural reservoirs of coronviruses and the potentially zoonotic source of viral pathogens.
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