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Purification and primary structure of galanin from the alligator stomach
Galanin-like immunoreactivity (6 pmol/g tissue) was detected by radioimmunoassay in an extract of the stomach of the alligator, Alligator mississipiensis, but the peptide was present only in lowExpand
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Identifying and Overcoming Matrix Effects in Drug Discovery and Development
Liquid chromatography/tandem mass spectrometry (LC-MS/MS) with electrospray ionization is a highly specific and sensitive analytical technique that has become the industry standard for quantifyingExpand
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Association of expression of XIAP-associated factor 1 (XAF1) with clinicopathologic factors, overall survival, microvessel density and cisplatin-resistance in ovarian cancer
XIAP-associated factor 1 (XAF1) was identified as a novel X-linked inhibitor of apoptosis (XIAP) binding partner that can reverse the anti-apoptotic effect of XIAP. XAF1 levels are greatly decreasedExpand
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Neuroendocrine peptides (NPY, GRP, VIP, somatostatin) from the brain and stomach of the alligator
Despite the important position of the reptiles in phylogeny, relatively few regulatory peptides from reptilian species have been characterized structurally. Neuropeptide Y was isolated from the brainExpand
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Purification and characterization of galanin from the phylogenetically ancient fish, the bowfin (Amia calva) and dogfish (Scyliorhinus canicula)
Galanin was purified to near homogeneity from an extract of the stomachs of the holostean fish, the bowfin and the elasmobranch fish, the European common dogfish. Bowfin galanin contains anExpand
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Prosomatostatin-I is processed to somatostatin-26 and somatostatin-14 in the pancreas of the bowfin, Amia calva
With the exception of the Agnatha (lampreys and hagfishes), somatostatin-14 is the predominant molecular form of somatostatin in the pancreas of species from all classes of vertebrates yet studied.Expand
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The status of Chinese medicine in reversing multi-drug resistance of hepatocellular carcinoma
Multi-drug resistance (MDR) is a major obstacle in the chemotherapy of hepatocellular carcinoma. Comparing with western reversal agents, traditional Chinese medicine have advantages of low cost,Expand
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BKCA CHANNEL ACT AS A NEGATIVE-FEEDBACK REGULATOR IN THE DEVELOPMENT OF COLD-INDUCED HYPERTENSION
Objectives Cold is an important factor contributing to the high incidence of hypertension. In order to explore the mechanisms of cold-induced hypertension. This study observed whether LargeExpand
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