Yunus Annayev

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The current consensus model for the circadian clock in mammals is based on a transcription-translation feedback loop. In this model, CRY and PER proteins repress their own transcription by suppressing the transactivator function of the CLOCK:BMAL1 heterodimer directly (physical model) and by facilitating post-translational modifications (chemical model).(More)
Yunus Annayev: Characterization of a new circadian clock gene Gm129 (Under the direction of Aziz Sancar) Circadian clock is a 24hr rhythmicity that controls behavioral, metabolic events in most of the organisms. It has been reported that around 10% of all transcripts in mice show circadian expression pattern. The circadian clock is regulated by core clock(More)
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