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Analysis of clinical features and early warning signs in patients with severe COVID-19: A retrospective cohort study
TLDR
The results could be helpful in the early detection of patients at risk for severe illness, enabling the implementation of effective interventions and likely lowering the morbidity of COVID-19 patients. Expand
Association between Alanine Aminotransferase and Growth Hormone: A Retrospective Cohort Study of Short Children and Adolescents
TLDR
GH secretion level was strongly negatively correlated with ALT in short children and adolescents and rhGH therapy could reduce ALT level over time. Expand
Low-density lipoprotein cholesterol levels are associated with insulin-like growth factor-1 in short-stature children and adolescents: a cross-sectional study
TLDR
This study demonstrated a nonlinear relationship between IGF-1 and LDL-C independent of other potential confounding factors, suggesting that circulating IGF- 1 may contribute to the regulation of LDL- C levels, thus meriting further investigation. Expand
Association between Insulin-Like Growth Factor-1 and Relative Skeletal Maturation: A Retrospective Cohort Study of Short Children and Adolescents
TLDR
There is a nonlinear relationship between IGF-1 and BA maturation in short children before and after growth hormone (GH) treatment, and these findings suggest that a low level of IGF- 1 may contribute to BA delay in shortChildren and adolescents. Expand
Association between Growth Hormone-Insulin-Like Growth Factor-1 Axis Gene Polymorphisms and Short Stature in Chinese Children
TLDR
The heterozygous genotypes of rs12515480 and rs6873545 of GHR gene were associated with decreased risk of GHD in Chinese children, consistent with those expected from Hardy-Weinberg equilibrium. Expand
A Retrospective Analysis of Patients with Short Stature in Eastern China between 2013 and 2019
TLDR
The present findings indicate that children with short stature need to be referred to a specialist centre to diagnose the cause of growth failure and that short children receiving rhGH therapy show a significant increase in height over time. Expand
Association between insulin‐like growth factor‐1 and systolic blood pressure in children and adolescents with short stature
TLDR
There is a nonlinear relationship between the IGF‐1 SDS and SBP in children with short stature and increased serum IGF‐ 1 levels were associated with elevated SBP when the IGF-1 levels reached the inflection point. Expand
Association between triglyceride glucose index and peak growth hormone in children with short stature
TLDR
It is found that the TyG index was significantly higher in the GHD group than in the non-GHD group, and a higherTyG index is associated with decreased peak GH in children with short stature. Expand
Association between serum uric acid and triglycerides in Chinese children and adolescents with short stature
TLDR
The present study identified the non-linear association of SUA and TG levels with short children and adolescents, based on BMI status, and suggests that health status should be considered for short stature children with high SUA levels, especially in children with a high BMI standard deviation score. Expand
Relationship between hemoglobin and insulin-like growth factor-1 in children and adolescents with idiopathic short stature
TLDR
It is demonstrated that Hb is associated with IGF-1 in Chinese children and adolescents with ISS, but when the concentration of Hb exceeded a certain range, with the increase of HB, IGF- 1 decreased instead. Expand
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