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Comparison between the efficacies of curcumin and puerarin in C57BL/6 mice with steatohepatitis induced by a methionine- and choline-deficient diet
Non-alcoholic fatty liver disease (NAFLD) is a prevalent disease, which features an abnormal accumulation of lipids inside hepatocytes. Steatohepatitis plays a critical role in the process resultingExpand
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  • Open Access
CRNDE, a long-noncoding RNA, promotes glioma cell growth and invasion through mTOR signaling.
The transcripts of the gene Colorectal Neoplasia Differentially Expressed (CRNDE) are recognized as long-noncoding RNAs (lncRNAs), which are expressed in specific regions within the human brain, andExpand
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Elevation of Peripheral BDNF Promoter Methylation Links to the Risk of Alzheimer's Disease
Brain derived neurotrophic factor (BDNF) has been known to play an important role in various mental disorders or diseases such as Alzheimer's disease (AD). The aim of our study was to assess whetherExpand
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  • Open Access
Integrated lipidomics and transcriptomic analysis of peripheral blood reveals significantly enriched pathways in type 2 diabetes mellitus
BackgroundInsulin resistance is a key element in the pathogenesis of type 2 diabetes mellitus. Plasma free fatty acids were assumed to mediate the insulin resistance, while the relationship betweenExpand
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Male-Specific Association between Dopamine Receptor D4 Gene Methylation and Schizophrenia
Objective The goal of our study was to investigate whether DRD4 gene DNA methylation played an important role in the susceptibility of Han Chinese SCZ. Methods Using the bisulphite pyrosequencingExpand
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Polymorphisms of DRD2 and DRD3 genes and Parkinson's disease: A meta-analysis.
Parkinson's disease (PD) is the second most common neurodegenerative disorder that affects ~2% of the population aged ≥65 years. The degeneration of dopamine neurons in the substantia nigraExpand
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Curcumin as a potential treatment for Alzheimer's disease: a study of the effects of curcumin on hippocampal expression of glial fibrillary acidic protein.
Curcumin, an agent traditionally utilized for its preventative action against tumorigenesis, oxidation, inflammation, apoptosis and hyperlipemia, has also been used in the treatment of Alzheimer'sExpand
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DNA methylation patterns of protein coding genes and long noncoding RNAs in female schizophrenic patients.
Schizophrenia (SCZ) is a complex mental disorder contributed by both genetic and epigenetic factors. Long noncoding RNAs (lncRNAs) was recently found playing an important regulatory role in mentalExpand
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A Giant Intradiaphragmatic Bronchogenic Cyst: Case Report and Literature Review
Bronchogenic cysts are congenital lesions developing during early embryogenesis. The intradiaphragmatic location is extremely rare. We present a giant bronchogenic cyst arising from the left crus ofExpand
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Effects of caffeic acid on learning deficits in a model of Alzheimer's disease.
Caffeic acid is a type of phenolic acid and organic acid. It is found in food (such as tomatoes, carrots, strawberries, blueberries and wheat), beverages (such as wine, tea, coffee and apple juice)Expand
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