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We investigated the potential association of 12 single nucleotide polymorphisms (SNPs) of nucleotide excision repair (NER) genes with risk of laryngeal cancer. A ratio of 1:1 matched case–control study was conducted. Conditional regression analysis indicated that subjects with ERCC1 rs11615 CC and C allele had an increased risk of laryngeal cancer compared(More)
STUDY DESIGN Retrospective, comparative study. OBJECTIVE To compare the effects of anterior rod-screw instrumentation and posterior pedicle screw instrumentation on sagittal balance in patients with Lenke type 5 adolescent idiopathic scoliosis (AIS). SUMMARY OF BACKGROUND DATA Lenke type 5 AIS is treated by anterior or posterior spinal fusion surgery.(More)
Between March 2003 and September 2007, 170 consecutive patients with lumbar degenerative disease were studied retrospectively. Eighty patients underwent posterior lumbar interbody fusion (PLIF group) with pedicle screw (PS) fixation, and 82 patients underwent posterolateral fusion (PLF group) with PS fixation. Eight patients were lost to follow-up. The(More)
STUDY DESIGN A retrospective study. OBJECTIVE The aim of this study was to compare clinical and radiological outcomes of anterior cervical corpectomy and fusion (ACCF) combined with artificial disc replacement (C-ADR) and ACCF combined with anterior cervical discectomy and fusion (ACDF) in patients with consecutive 3-level cervical spondylotic myelopathy(More)
We postulated that the lowest instrumented vertebra (LIV) can be determined based on the apical vertebra. Seventy-two Lenke type 1 patients (average age: 13.6 years) receiving posterior spinal fusion were randomised into two groups. In group A, the apical vertebra was used to determine the LIV and in group B the neutral vertebra was used. All patients had(More)
STUDY DESIGN Retrospective. OBJECTIVE To compare the occurrence of the crankshaft phenomenon in patients with adolescent idiopathic scoliosis (AIS) who underwent hybrid, consecutive pedicle screw or interval pedicle screw instrumentation for posterior spinal fusion. SUMMARY OF BACKGROUND DATA Scoliosis may progress after posterior spinal fusion in(More)
BACKGROUND Degeneration of intervertebral disks in the lower lumbar spine is associated with significant structural alterations. Finite element model has been widely used in the study of spinal mechanical behaviors. Our study used this technique to characterize the motional influence to the double-level (L4-5 and L5-S) degeneration. METHODS AND RESULTS(More)
AIMS This study aims to investigate the effect of allicin on motor functions and histopathologic changes after spinal cord injury and the mechanism underlying its neuroprotective effects. MAIN METHODS The motor function of rats was evaluated with the Basso, Beattie, and Bresna test. Histopathologic changes were evaluated by hematoxylin and eosin and Nissl(More)
OBJECTIVE To study the effect of the thoracoplasty on the pulmonary function after the posterior scoliosis correction operation. METHODS From June 2001 to June 2010, 60 thoracic scoliosis patients (24 males, 36 females) were collected. Their average age was 17.6 ± 5.0 years. All patients underwent posterior 3-dimensional operation and thoracoplasty. The(More)
OBJECTIVE To investigate the expression of breast cancer metastasis suppressor 1 (BRMS1) gene protein and the expression of BRMS1 gene promotor area methylation in supraglottic cancer and to evaluate its clinical significance. METHOD The expression of BRMS1 protein and BRMS1 gene promotor area methylation were examined by using Western blotting method and(More)