Yung-Chie Lee

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Epidermal growth factor receptor (EGFR) is a novel target for therapy in subsets of non-small cell lung cancer, especially adenocarcinoma. Tumors with EGFR mutations showed good response to EGFR tyrosine kinase inhibitors (TKIs). We aimed to identify the discriminating capacity of immunohistochemical (IHC) scoring to detect L858R and E746-A750 deletion(More)
BACKGROUND Simvastatin has been shown to ameliorate pulmonary hypertension by several mechanisms in experimental animal models. In this study, we hypothesized that the major benefits of simvastatin in pulmonary hypertension occur via the heme oxygenase-1 pathway. METHODS Simvastatin (10 mg/kgw/day) was tested in two rat models of pulmonary hypertension(More)
INTRODUCTION Survival after cadaveric lung transplantation (LTx) in respiratory failure recipients who were already dependent on ventilation support prior to transplantation is poor, with a relatively high rate of surgical mortality and morbidity. In this study, we sought to describe the short-term outcomes of bilateral sequential LTx (BSLTx) under(More)
18 F-FDG PET has been widely used for staging non-small cell lung cancer. We report herein a case of right-middle-lobe adenocarcinoma with multiple 18 F-FDG-avid lymph nodes in mediastinum. The patient is a 73-year-old housewife who has received right middle lobe lobectomy and extensive dissection of mediastinal lymph nodes. Pathologic examination of all(More)
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