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Different from traditional multiple backbones continuum manipulators, a novel elephant-trunk manipulator, called ET Arm, is design and developed. The ET Arm is composed of one or two segments (called muscle segment). The muscle segment includes three reduced motors, three flexional rods connected to screw, multiple disks, springs and wired bellows. When any… (More)
An unexpected R(2)AlCl-mediated ring-opening reaction of oxacycles for the formation of all-carbon quaternary centers was discovered, and a possible mechanism is proposed. The developed chemistry provides a concise approach to synthesize structural diverse of dolastane-type compounds.
The aim of the project was to assemble two optimum solid lipid nanoparticle (SLN) formulations for oral delivery of loperamide (LPM) to treat different types of diarrhea, and to evaluate their release profiles in vitro and pharmacokinetic properties in vivo. In this work, glyceryl trimyristate (Dynasan 114) nanoparticles containing the drug LPM and sodium… (More)