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Preoperative Neutrophil-Lymphocyte Ratio Before Platelet-Lymphocyte Ratio Predicts Clinical Outcome in Patients With Cervical Cancer Treated With Initial Radical Surgery
TLDR
The preoperative NLR, but not PLR, may be used as a potential and easy biomarker for survival prognosis in patients with cervical cancer receiving initial radical hysterectomy with pelvic lymphadenectomy.
Overexpression of Wnt7a Is Associated With Tumor Progression and Unfavorable Prognosis in Endometrial Cancer
TLDR
Overexpression of Wnt7a may contribute to the progression of endometrial cancer and thus may serve as a new biomarker to predict the prognosis of endometricrial cancer.
Ubiquitin-specific protease 22: a novel molecular biomarker in cervical cancer prognosis and therapeutics
TLDR
It is suggested that USP22 overexpression may be associated with poor prognosis in cervical cancer, and may represent a novel prognostic biomarker or a target for improving the treatment efficiency of patients with cervical cancer.
Overexpression of ANCCA/ATAD2 in endometrial carcinoma and its correlation with tumor progression and poor prognosis
TLDR
It is identified that ANCCA protein expression as a novel independent poor prognostic indicator in EC was an independent prognostic factor for both OS and DFS of patients with EC.
LAPTM4B polymorphisms is associated with ovarian cancer susceptibility and its prognosis.
TLDR
Findings indicate that the LAPTM4B 2 allele may be a risk factor for ovarian cancer and may play an important role in genetic susceptibility to ovarian cancer.
Betulin induces apoptosis of HeLa cell lines in vitro and its possible mechanism
TLDR
In a certain concentration range, betulin can inhibit the proliferation of HeLa cells and induce the apoptosis in vitro, and this effect may be associated with the up-regulated expressions of caspase-3 and PARP proteins.
Quercetin-Modified Metal-Organic Frameworks for Dual Sensitization of Radiotherapy in Tumor Tissues by Inhibiting the Carbonic Anhydrase IX.
TLDR
The mechanisms of alleviating hypoxia-induced resistance and sensitizing tumor tissues to improve cell apoptosis from radiation were found to suppress CA IX expressions by the decomposition product from Zr-MOF and boost the sensitivity by QU in radiation therapy.
Correlation of TNFAIP8 overexpression with the proliferation, metastasis, and disease-free survival in endometrial cancer
TLDR
It is suggested that TNFAIP8 may be used as a prognostic marker for the recurrence of EC, and its promotion of the proliferation and metastasis in EC may be due to its mediation of Ki-67 and MMP9.
MicroRNA-595 sensitizes ovarian cancer cells to cisplatin by targeting ABCB1
TLDR
The data suggested that miR-595 acted a tumor suppressor role in ovarian cancer development and increased the sensitivity of ovarian cancer to cisplatin.
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